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妊娠期肝脏疾病的临床特点分析

Analysis of Clinical Characteristics of Pregnant women's Liver Diseases
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摘要 目的:探讨妇女妊娠后引发的肝脏疾病的特点。方法:对金华市区4所医院近6年内收治的1775例妊娠期肝脏疾病的临床特点进行回顾分析,前3年为A组(539例),后3年为B组(1236例)。比较两组临床表现和对孕产妇、胎儿的影响,并与同期住院的正常孕产妇(24590例)进行比较。结果:妊娠期肝内胆汁淤积症、皮肤瘙痒,B组较A组明显增加(P<0.05),而病毒性肝炎、妊娠剧吐、子痫前期、子痫所占比例有所下降(P<0.05)。与正常妊娠组比,肝病组胎膜早破、产后出血、弥散性血管内凝血、早产、流产、胎儿宫内窘迫、死胎、新生儿窒息、新生儿死亡均极显著地增加(P<0.01)。结论:近3年妊娠期肝脏疾病种类与前期有所不同;妊娠期肝病对孕产妇和胎儿有显著影响(P<0.05)。临床医生要高度重视,并进行有效的预防和治疗。 Objective: To discuss the characteristics of liver diseases in pregnancy women in order to improve its prevention and treatment and guarantee the reproduction health. Methods: 1 775 pregnancy women with liver diseases of four hospitals in Jinhua urban district in the past six years were reviewed retrospectively. They were divided into two groups, Group A(539cases)of the first three years and Group B (1 236 cases) of the later three years. The clinical manifestation and the effect for pregnacy women and their fetus of two groups were compared and 1 775 cases also compared with all patients admitted at the same time. Results: The percentage of ICP and pruritus in Group B raised noticeably compared with that in Group A (P〈0.05). Whereas percentage of virus hepatitis, severe pregnancy vomit, early gravid arum or gravid arum in Group B decreased greatly (P〈0.05). Compared weith normal group, clinical symptoms as DIC, premature delivery, abortion, hard-pressed in womb, fetal death, newborn suffocation, etc. increased significantly (P〈0.01). Conclusion: During the recent three years the types of liver disease in pregnancy had changed. Liver diseases in pregnancy has greatly effect on pregnancy women and their fetus. The rapist should pay highly Sattention to the harmfulness of liver diseases in pregnancy and conduct effective prevention and treatment measures.
出处 《生殖与避孕》 CAS CSCD 北大核心 2005年第7期414-417,共4页 Reproduction and Contraception
关键词 妊娠 肝脏疾病 妊娠并发症 pregnancy hepatopathy pregnancy complication
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