摘要
目的研究合并慢性肾功能不全冠心病患者植入冠状动脉(冠脉)内药物洗脱支架的预后。方法连续463例接受冠脉内药物洗脱支架术治疗的患者中,175例合并慢性肾功能不全,288例肾功能正常(对照组)。记录患者一般临床资料、冠脉造影和支架术情况,分析随访期心脏事件、心绞痛发生率和心源性死亡率。结果平均随访(12.4±4.7)月后,肾功能不全组与对照组的心脏事件发生率(4.6%vs3.1%,P=0.422)和心绞痛复发率(6.3%vs8.3%,P=0.419)无明显差异,但肾功能不全组的心源性死亡率显著高于对照组(2.9%vs0.4%,P=0.031)。结论慢性肾功能不全是增加冠脉支架术后死亡率的独立危险因素。
Objective To study the effects of drug-eluting stents in patients with chronic renal dysfunction. Methods Four hundred and sixty-three consecutive patients underwent percutaneous coronary intervention with drugeluting stents： 175 patients with chronic renal dysfunction, and 288 without it. Baseline clinical characteristics, coronary angiographic and percutaneous coronary intervention characteristics, recurrence of angina and occurrence of cardiac events during follow-up were recorded. Results During follow-up （12.4 ± 4.7 months） , the cardiac event rate and the recurrence of angina did not significantly differ between the patients with and without chronic renal dysfunction （4.6% vs 3.1% , P = 0. 422 ; 6.3% vs 8.3% , P =0. 419）. But the mortality was markedly increased in patients with rather than without chronic renal dysfunction （2. 9% vs 0. 4% , P = 0. 031 ）. Conclusion Chronic renal dysfunction is an independent risk factor of death in patients undergoing stenting.
出处
《上海交通大学学报（医学版）》
CAS
CSCD
北大核心
2006年第1期87-89,共3页
Journal of Shanghai Jiao tong University:Medical Science
关键词
药物洗脱支架
慢性肾功能不全
冠心病
drug-eluting stent
chronic renal dysfunction
coronary heart disease
