摘要
目的:探讨手术配合高压氧(HBO)治疗精索静脉曲张(VC)所致不育的临床疗效及机制。方法:将VC不育患者96例随机分成两组,A组(40例)为手术配合高压氧治疗组,B组(56例)为单纯手术组。结果:两组在精子密度、精子活率、精子活力和正常形态精子数、睾酮、配偶受孕率方面都有显著改善(P<0.01或P<0.05),且A组改善优于B组(P<0.05)。A组患者卵泡刺激素、黄体生成素在治疗后较治疗前显著下降(P<0.05)。A组精子穿透卵子百分率(SPA值)改善优于B组(P<0.05)。A组治疗后配偶受孕时间较B组提前(P<0.05)。结论:手术配合HBO治疗VC不育患者较单纯手术治疗更有效改善生殖内分泌激素失调,提高精子质量,提高SPA值,增加受孕率,缩短治疗后受孕时间。
Objective： To explore the therapeutic effects of combination of varicocelectomy with hyperbaric oxygenation （HBO） in treating infertile patients with varicocele. Methods： Ninty-six patients were randomly divided into two groups： 40 patients in group A treated by varicocelectomy with HBO, and 56 in group B treated by solitary varicocectomy. Results ： The sperm denisty, sperm motility, sperm vigor, normality, serum testosterone, the pregnant rate of patient＇s spouses were improved respectively in both two groups （P 〈0.01 or P 〈0. 05 ）, and group A had better results than group B （ P 〈 0.05 ）. LH, FSH in group A decreased significantly after the therapy. Group A had higher sperm penetration asay （SPA） percentages than group B（P〈0.05）, and the pregnant time of patient＇s spouses in group A was earlier than that in group B（ P 〈 0. 05）. Conclusion： Varicocelectomy with HBO can more effectively regulate reproductive hormone, improve semen quality, SPA index and pregnant rate than solitary varicecelectomy in treating infertile patients with varicocele and can markedly shorten the pregnant time.
出处
《中华男科学杂志》
CAS
CSCD
2006年第1期46-49,共4页
National Journal of Andrology
