摘要
目的:探讨抗内皮细胞抗体(AECA)和血小板生成素(TPO)测定在鉴别特发性血小板减少性紫癜(ITP)和系统性红斑狼疮(SLE)中的临床意义。方法:用ELISA法分别测定76例ITP患者、41例SLE患者及50例正常人血清中的AECA和TPO水平。结果:SLE组、ITP组患者血清AECA水平明显高于正常对照组(P<0.01);SLE组患者血清AECA水平显著高于ITP组(P<0.01);ITP组患者血清TPO水平与正常对照组无显著差异(P>0.05),而SLE组血清TPO水平显著高于ITP组患者和正常对照组(P<0.01)。结论:血清AECA和TPO的测定在鉴别诊断ITP和SLE中有显著的临床意义。
AIM： To study the clinical significance of determining serum anti - endothelial cell antibodies （AECA） and thrombopoietin （TPO） in the differential diagnosis of idiopathic thrombocytopenic purpura （ITP） and systemic lupus erythematostts （SLE）. METHODS： Serana AECA and TPO in 76 patients with ITP, 41 patients with SLE and 50 normal individuals were detected by ELISA method. RESULTS： Serum AECA level in SLE and ITP was much higher than that in normal group （ P 〈 0.01 ）. AECA in SLE was much higher than that in ITP （ P 〈 0.01 ）. TPO level in ITP was in the same range as that in normal controls （ P 〉 0.05）, but serum TPO level in SLE was much higher than that in ITP and normal groups （ P 〈 0.01 ）. CONCLUSION： Detecting serum AECA and TPO might be helpful for differentiating SLE and ITP.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
2006年第1期128-130,共3页
Chinese Journal of Pathophysiology
关键词
抗内皮细胞抗体
红斑狼疮
血小板生成素
紫癜
血小板减少性
Anti - endothelial cell antibodies
Lupus erythematosus, systemic
Thrembopoietin
Pmrpura, thrombocytopenic, idiopathic
