摘要
目的研究先兆流产不良妊娠结局的危险因素,为先兆流产的干预提供临床依据。方法随访252例先兆流产妇女的妊娠结局,通过病史询问和理化检查获得并登记影响妊娠结局的可能因素。结果20·23%先兆流产的患者最终发生自然流产,不良妊娠率为27·78%。在不良妊娠结局组中,高龄妊娠、低收入、污染接触职业、早期阴道流血、阴道多量流血、宫内大血肿的发生率显著高于良好妊娠结局组(P<0·05)。流产史、夫妻关系不和、吸烟、酗酒、吸毒、流产家族史和配偶冶游史在两组之间的差异无显著性。Logistic回归分析:高龄妊娠、低收入、宫内大血肿及早期阴道流血进入回归方程。其中早期阴道流血OR值为2·542,P<0·01,其次,宫内大血肿OR值为2·379,P<0·05,具有统计学意义。高龄妊娠和低收入的OR值分别为1·764和1·930,但P>0·05,不具有统计学意义。结论先兆流产不良妊娠结局发生率较高,早期阴道流血、宫内大血肿是不良妊娠结局独立危险因素,高龄妊娠与低收入是可能的危险因素。
Objective To explore the risk factors of bad outcome of threatened miscarriage and provide clinical evidence for intervention of threatened miscarriage. Methods Obtain and document the possible factors contributing to the pregnancy outcome by history query and physical and chemical examination in 252 women with threatened miscarriage and follow their pregnancy outcome. Results 20.23% women with threatened miscarriage ended their pregnancy because of spontaneous abortion and 27.78% women got bad outcome. The incidence of old age, low income, pollution contact career, early virginal hemorrhage, heavy virginal hemorrhage and intrauterine haematoma in the group with bad outcome was significantly higher than that in the group with good outcome （P 〈 0.05）. There is no significant difference in individual or family history of abortion, unpleasant couple relationship, smoking, drinking and drug abuse and history of venereal disease in spouse between the two group. Logistic regression analysis showed that old age, low income, intrauterine haematoma and early virginal hemorrhage were left in regression equation. There has statistical significance in early virginal hemorrhage （R = 2.542, P 〈 0.01） and intrauterine haematoma （OR = 2.379, P 〈 0.05）, however, there has no statistical significance in old age （OR = 1.764, P 〉 0.05） and low income （OR = 1.930, P 〉 0.05）. Conclusion The incidence of bad outcome in women with threatened pregnancy was high. Early virginal hemorrhage and intrauterine haematoma were independent risk factors of bad outcome for threatened miscarriage while old age and low income acted as possible risk factors.
出处
《医学研究杂志》
2006年第1期28-30,共3页
Journal of Medical Research
