摘要
进行了“GS-1”农药的急性毒性和亚慢性毒性试验。结果表明,“GS-1”急性毒性有明显的性别差异。雄性大鼠属于低毒范围,雌性大鼠属于中等毒范围。亚慢性毒性显示60mg/kg剂量组,动物出现中毒症状并引起部分动物死亡,白细胞计数降低,肝体比增大,肝细胞脂肪变性。亚慢性毒性试验的最大无作用剂量(MNL)为20mg/kg。
A study on the acute and subchronic toxicity of pesticide “GS 1” was carried out with the following results: In acute toxicity test, the toxicity of “GS 1” showed difference in male and female rats with, LD 50 being 1330 mg/kg and 348 mg/kg respectively. With a dose over 60 mg/kg, adverse effects were observed, including poisonous symptoms(e.g.dying, decreasing in the number of white blood cells, increasing in liver weight ratio). The maximum non effect level(MNL) of the GS 1 was 20 mg/kg.
出处
《南京医科大学学报(自然科学版)》
CAS
CSCD
1996年第6期546-548,共3页
Journal of Nanjing Medical University(Natural Sciences)