摘要
为探讨弥漫性间质性肺疾病纤维结合蛋白变化及其临床意义，对弥漫性间质性肺疾病患者应用火箭电泳方法检测支气管肺泡灌洗液中纤维结合蛋白。结果显示，支气管肺泡灌洗液中纤维结合蛋白明显高于对照组（Ｐ＜０．０１）。相关性分析表明，纤维结合蛋白与支气管肺泡灌洗液中细胞数有一定相关性（ｒ＝０．８９０５，Ｐ＜０．０１）。提示纤维结合蛋白在弥漫性间质性肺疾病的病理机制中起着重要作用。
To investigate the changes of fibronectin(Fn) and its clinical significance in PDID, we determined the Fn in bronchiolar alveolar lavage fluid(BALF) in patients with PDID on pochet electrophoresis. The results showed that Fn levels in BALF in the study group patients were significantly higher than those in the control group( P <0.01). Correlation was found between Fn and cell count in BALF( r=0.8905,P <0.01). It was suggestive that Fn might play an important role in the development of pulmonary fibrosis in PDID.
出处
《南京医科大学学报（自然科学版）》
CAS
CSCD
1996年第5期449-451,共3页
Journal of Nanjing Medical University(Natural Sciences)
