摘要
选择25例慢性肝病(慢迁肝、慢活肝、肝硬化)患者。取空腹静脉血常规制片,透射电镜 观察,结果发现肝硬化和慢活肝患者血小板形态变化较多,细胞内颗粒减少,管道系统扩大并增生, 易见异常颗粒等结构改变,其在ADP诱导下,聚集体分别为75.9%和70.28%,多数细胞间有桥状 联系而模糊不清,甚至细胞间隙消失,细胞膜融合。
The fasting venous blood smear of 25 patients with chronic hepatic disease including chronic persisting hepatitis (CPH) .chronic active hepatitis (CAH) and cirrhosis were observated with transmission electron microscope. It was found that the blood platelet of patients with cirrhosis and CAH had quite more structure and shape changes:intercellular granule decreased,canal system extended and proliferated;abnormal granule easily to seen and so on. Under the ADP induced the aggregating body were respectively 75.9% and 70.28%. Most of intercellular there were bridge connection but which were blurred,even intercelluar space disappear and cytomembrane fusion.
关键词
肝疾病
血小板
超微结构
聚集功能
Chronic hepatic disease Blood platelet Ultrastructure Aggregating function