期刊文献+

老年急性冠脉综合征的临床治疗 被引量:1

Therapy for acute coronary syndrome in the elderly
暂未订购
导出
摘要 目的探讨老年急性冠脉综合征(ACS)的临床治疗。方法总结56例60~87岁,平均(73.2±6.7)岁ACS患者临床、冠脉造影和经皮冠脉介入(PCI)、非体外循环下冠脉搭桥(OPCAB)资料。结果①80.4%(45例)有多项危险因素;②冠脉造影85.7%(48例)为多支、多处严重狭窄,15例心电图无ST段改变的不稳定型心绞痛者为多支病变;③42例51支血管置入60枚支架,8例患者行OPCAB。结论心血管病危险因素和发病时临床表现是老年ACS重要诊断依据。PCI和OPCAB治疗老年ACS疗效和安全性良好。 Objective To explore the effects of percutaneous coronary intervention (PCI) and off-pump coronary artery bypass grafting (OPCAB) in the elderly with acute coronary syndrome (ACS). Methods Fifty-six patients aged 60-87 years (73.2 ± 6. 7 years) with ACS undergoing coronary angiography and PCI or OPCAB were analyzed. Results Forty-five cases (80.4% ) had multiple cardiac risk factors except age and sex, The significant lesions (stenosis ≥ 50% ) were detected in all patients, The severe stenosis of multi-vessel was found in 48 patients ( 85.7% ). The 60 stents were implanted to 51 vessels of 42 patients respectively and OPCAB were successfully performed in 8 patients with a mean age of 75.3 ± 6. 2 years. Conclusions It is suggested that cardiac risk factors and the symptoms on attack are very important evidences in diagnosing ACS in the elderly. Therapy with PCI or OPCAB is beneficial and safe for the elderly with ACS.
出处 《实用老年医学》 CAS 2006年第1期31-33,共3页 Practical Geriatrics
关键词 心肌梗死 心绞痛 不稳定型 血管成形术 经腔 经皮冠状动脉 老年人 Myocardial infarction Angina, unstable Angioplasty, transluminal, percutaneous coronary Aged
  • 相关文献

参考文献8

二级参考文献23

  • 1Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coil Cardiol,2000, 36: 970-1062.
  • 2Shen WF, Zhang RY, Shen Y, et al. Optimal timing for coronary stenting in unstable angina. Chin Med J, 2001, 114: 59-61.
  • 3Fragmin and fast revascularisation during instability in coronary artery disease investigators. Invasive compared with non-invasive treatment in unstable coronaryartery disease: FRISC Ⅱ prospective randomised multicentre study.Lancet, 1999, 354: 708-715.
  • 4Cannon CP, Weintraub WS, Demopoulos LA, et al. Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein H b/Ⅲ a inhibitor tirofiban. N Engl J Med,2001, 344: 1879-1887.
  • 5Ronner E, Boersma E, Laarman GJ, et al. Early angioplasty in acute coronary syndromes without persistent ST-segment elevation improves outcome but increases the need for six-month repeat revascularization: an analysis of the PURSUIT Trial. J Am Coll Cardiol, 2002, 39: 1924-1929.
  • 6Boden WE, McKay RG. Optimal treatment of acute coronary syndromes-an evolving strategy. N Engl J Med, 2001, 344: 1939-1942.
  • 7Kleiman NS, Lincoff AM, Flaker GC, et al. Early percutaneous coronary intervention, platelet inhibition with eptifibatide, and clinical outcomes in patients with acute coronary syndromes. PURSUIT Investigators. Circulation,2000, 101: 751-757.
  • 8Stone PH, Thompson B, Zaret BL, et al. Factors associated with failure of medical therapy in patients with unstable angina and non-Q wave myocardial infarction: a TIMI Ⅲ B database study. Eur Heart J, 1999, 20: 1084-1093.
  • 9Al-Ruzzeh S, George S, Yacoub M, et al. The clinical outcome of off-pump coronary artery bypass surgery in the elderly patients. Eur J Cardiothorac Surg,2001,20:1152-1156.
  • 10Koutlas TC, Elbeery JR, Williams JM, et al. Myocardial revascularization in the elderly using beating heart coronary artery bypass surgery. Ann Thorac Surg, 2000,69:1042-1047.

共引文献2718

同被引文献4

  • 1Gum PA, Kottke-Marchant K,Welsh PA, et al. A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease [J]. J Am Coil Cardiol, 2003, 41(6) :961-965.
  • 2Eikelboom JW, Hirsh J, Weitz JI, et al. Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events [ J ]. Circulation, 2002,105 ( 14 ) : 1650-1655.
  • 3Minuz P, Patrignani P, Gaino S, et al. Determinants of platelet activation in human essential hypertension [ J ]. Hypertension, 2004 ,43 ( 1 ) :64-70.
  • 4谈世进,杨建芬,李胜前.氯吡格雷联合阿司匹林对老年不稳定型心绞痛患者血小板活化的临床干预研究[J].实用老年医学,2007,21(4):243-245. 被引量:5

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部