摘要
【目的】评价早期干预降低早产儿脑瘫发生率的效果。【方法】出生或就医于29个协作单位存活的早产儿2684例,胎龄小于37周,除外先天畸形和遗传代谢性疾病,分为两组:研究开始前1年内出生和研究后出生的家长不愿参加早期干预指导的早产儿为常规育儿组(常规组),研究开始后出生的家长积极参加早期干预指导的早产儿为早期干预组(干预组)。两组婴儿数目相近。干预组早产儿出院后于家中在早期教育的基础上接受按摩、被动体操和运动训练。常规组只接受常规保健指导。【结果】两组孕母并发症、平均胎龄和出生体重、小于胎龄儿和适于胎龄儿的比例、单胎和多胎的比例、胎内窘迫、胎膜早破发生率、阿氏评分、生后窒息、新生儿缺氧缺血脑病轻重比例和颅内出血的发生率差异均无显著性(P>0.05),说明两组有可比性。1岁时脑瘫发生率干预组为9.4‰(13/1 390),常规组为35.5‰(46/1294),两组差异有非常显著性(P<0.0001)。【结论】指导父母对早产儿出院后开始进行早期干预可降低脑瘫发生率。
[Objective] Evaluation of effects of early intervention on lowing incidence of cerebral palsy of premature infants. [Methods] 2 684 cases of survived premature infants, gestational age under 37 weeks, excluding those with congenital deformity and hereditary metabolic diseases, born or treated in 29 collaborative units were classified into two groups： routine care group includes all premature infants born within one year before beginning of research and premature infants born after beginning of research whose parents did not want to receive early intervention, intervention group includ ed all premature infants whose family actively participate in early intervention after beginning of research. The numbers of infants in the two groups were quite close. The infants of intervention group received massage, exercise and motor training on basis of early education at home after discharge from hospital. The infants of normal care group received only conventional baby care. [Results] In the two groups, no significant differences （P〉0.05） were found in complications of pregnant mothers, average gestational age and birth weight, proportion of small for gestational age （SGA） and appriate for gesrational age （AGA）, proportion of single and multiple births, fetal stress, postnatal asphyxia, Apgar Score, incidence of neonatal HIE and intracranial hemorrhage. These indicate that the two groups were comparable. At one year of age, the incidence of cerebral palsy was 9.4‰（ 13/1 390） in the intervention group and 35.5‰（46/1 294） in the routine care group（P 〈0.0001）. [Conclusion] Instruct the parents to carry out intervention of premature infants beginning from discharge can reduce the incidence of cerebral palsy.
出处
《中国儿童保健杂志》
CAS
2006年第1期42-45,共4页
Chinese Journal of Child Health Care
基金
中国优生优育协会摇篮工程(2000)
关键词
早产
婴儿
早期干预
脑瘫
prematurity
infants
early intervention
cerebral palsy
