摘要
目的观察糖尿病合并脑梗死与血脂异常的相关性。方法分析66例糖尿病患者和30例正常对照的血糖和血脂。结果糖尿病无血管并发症组与对照组的血脂比较,仅有甘油三酯(TG)、载脂蛋白B(apoB)升高,载脂蛋白A-Ⅰ(apoA-Ⅰ)、apoA-Ⅰ/apoB下降有显著性差异(P<0.05),其他血脂改变无显著性差异;糖尿病合并脑梗死组与对照组比较,血脂及脂蛋白改变均有非常显著性差异(P<0.01);糖尿病合并脑梗死组与无血管并发症组比较,空腹血糖(FBG)、糖化血红蛋白(HbA1c)、TG、低密度脂蛋白胆固醇(LDL-ch)、apoB、apoA-Ⅰ/apoB、脂蛋白a(LPα)等有显著性差异(P<0.05),其中LPα升高、病程延长更显著(P<0.01)。结论糖尿病患者脑梗死的发生与血脂异常具有一定的相关性。
Objective To observe the relativity between cerebral infarction and dyslipidemia in patients with diabetes mellitus （DM）. Methods The blood glucose and lipid of 66 DM cases and 30 normal healthy persons （as control group） were tested. Results In the blood lipids of the diabetes group without vascular disease, only densities of triglyceride （TG）, apolipoprotein A-Ⅰ（apoA-Ⅰ）, apolipoprotein B （apoB）, apoA-Ⅰ/apoB changed significantly compared with the control group （ P〈0.05）, others without signifi- cant change. But blood lipids level of cerebral infarction group was significantly higher than that of the control group （P〈0.01）. In DM group, the patients with cerebral infarction had higher fasting blood glucose （FBG）, glycosylated hemoglobin Alc （HbAlc）, TG, low density lipoprotein cholesterol （LDL-ch）, apoB, α-lipoprotein （LPα）, but lower apolipoprotein A1 （apoA1） and apoA- Ⅰ / apoB than those of the without vascular disease group （P 〈0.05 or P〈0.01 ）. Conclusion Dyslipidemia has some relativity with the cerebral infarction of DM.
出处
《中国康复理论与实践》
CSCD
2005年第12期1028-1029,共2页
Chinese Journal of Rehabilitation Theory and Practice
