摘要
糖尿病的治疗目前集中于细胞的替代疗法。供体器官的短缺激发了对如何产生beta细胞的研究。目前,胰岛的扩增,胰岛的异种移植,人胰岛细胞系的开发,干细胞的分化都是热点。干细胞的治疗包括胚胎干细胞和成体干细胞。本文讨论干细胞向胰腺beta细胞分化的各种可能性。
Curative therapy for diabetes mellitus mainly implies replacement of functional insulin-producing pancreatic cells. However, shortage of donor organs spurs research into alternative means of generatlng-cells from islet expansion, encapsulated islet xenografts, human islet cell-lines, and stem cells. Both embryonic stem cells and adult stem cells have been used to generate surrogate cells. This paper discussed the possibilities of the differentiation from stem cells to pancreatic beta cells.
出处
《中国科学基金》
CSCD
北大核心
2006年第1期15-18,共4页
Bulletin of National Natural Science Foundation of China
