摘要
目的：观察急性肺栓塞病程2周以后，溶栓加抗凝和单纯抗凝临床效果比较。方法：将50例肺栓塞病程〉2周的病人分为A、B两组。A组用250ml。生理盐水加尿激酶200000～500000u，低分子肝素钙5000u皮下注射，1次／12h，连用7d，于停用低分子肝素钙前3d开始口服华法令，疗程6个月；B组仅应用低分子肝素钙及华法令，方法同A组。观察临床症状、体征、心脏彩超、肺通气灌注显像及螺旋CT检查的变化。结果：A组总有效率为50％，B组总有效率为40％，两者比较P〉0．05。结论：急性肺栓塞病程〉2周，小剂量溶栓加抗凝与单纯抗凝无显著差别，为减少出血风险选择单纯抗凝治疗。
Objective To compare the efficacy of intravenous thrombolytic therapy in small dose of urokinase and anticoagulation alone for 2-week acute pulmonary embolism. Methods Fifty patients with 2-week acute pulmonary embolism were randomly divided into two groups （A and B）. Twenty patients in group A were given urokinase plus low molecular heparin and thirty patients in group B were given anticoagulant therapy alone. Results The total effective rate of group A was 50% and it was not significantly higher than that of group B （40%）. Conclusion Anticoagulant alone therapy is a better selection than small close of UK to treat 2-week acute pulmonary embolism.
出处
《实用诊断与治疗杂志》
2006年第2期88-89,共2页
Journal of Practical Diagnosis and Therapy
关键词
急性肺栓塞
尿激酶
静脉溶栓
抗凝
Urokinse
pulmonary embolism
intravenous thrombolysis
