摘要
报告有特异性诊断依据的39例狂犬病患者进行抗狂犬病毒精蛋白抗体检测。血清总阳性率为97．44％（38／39）．但在前驱期和兴奋期仅为35．90％（14／39），麻痹期为刘．60％（35／37）。脑脊液总阳性率为40％（6／5）．在前驱期和兴奋则为33．33％（1／12）．麻痹期为75％（3／1）．所有患者均未得到保护而发病。研究提示，这冲抗体是病程后期的免疫应答．抗体效价也有一个由低到高的过程，可作为狂犬病的诊断依据之一。它的出现可能加速病程．即称作“早期死亡现象”。
Tests of the antibody against the glycoprotein of rabies virus in 39 specific-diagnosedpatients with rabies are reported in this paper. The total positive proportion in sera was 97. 44 % (38/39 ). and the positive proportion in the prodromal and furious periods was 35. 9O54 (14/39), and 94.6o5i (35/37) in the paralytic period. The total positive proportion in CSP was 10% (6/15), and theproportion ih the prodromal and furious pcriods was 33. 33% (4/12), and 75. 00% (3/4) · in theparalytic pcriod. All patients had not been protected. This study indicates that this antibody is a latc.immune response in the course of the disease. The titer of this antibody has a process of increase. andthus could be regarded as one of the dtagnosis criterta. The presence of this antibody could deterioratethe discase, which is Called ″ the early-death phenomenon″.*: The antibody against glycoprotein of rabies virus of onc case was positive both in the furiousand paralytic period.
出处
《泸州医学院学报》
1996年第1期1-5,共5页
Journal of Luzhou Medical College
基金
四川省科委科研基金
关键词
狂犬病
抗狂犬病毒
糖蛋白
抗体
免疫应答
Rabies, Antibody against the glycoprotein of rabies viruse, Immune response, Dignoses,Early-death phenomenon
