摘要
目的探讨肺炎克雷伯菌肠炎的临床特征、药敏情况,为合理治疗提供依据。方法对经粪便细菌培养证实的43例迁延性、慢性肺炎克雷伯菌肠炎的资料进行分析。结果43例中,3岁以下婴幼儿占95.3%,1岁以下婴儿占69.8%。肺炎克雷伯菌对亚胺培南敏感率100%,哌拉西林/舒巴坦钠敏感率97.7%,对儿科较少用的庆大霉素、妥布霉素、环丙沙星、左氧氟沙星的敏感率为60.5%￣76.7%,对常用的青霉素及头孢菌素类几乎均不敏感。根据药敏试验结果选择抗生素,加用贝飞达,疗效满意。结论克雷伯菌易引起婴幼儿迁延性、慢性肠炎,且临床症状不典型;克雷伯菌有部分为产ESBLs菌株,对一般抗生素不敏感,应选用敏感抗生素及调整肠道微生态。
Objective To investigate the clinical characteristics of pneumonic Klebsiella enteritis and the sensitivity to drug theraoy, in order to offer a method for reasonable therapy for Klebsiella inection, Methods 43 eases of chronic prolonged enteritis cause by pneumonic Klebsiella which proved by stool bacterial culture, the data were analysed. Results Among 43 cases, infant under three years old dominate 95,3%, infant under one years old 69.8%. Pneumonic Klebsiella sensitive rate to subamin 100%. Piperacillin sulbaetam sodium sensitive rate 97.7%, sensitive rate in pediatric rarely use drug such as Gentamicin, Tobramycin, Ciprofiosacin, Levofloxacin are 60.5% -76.7%,neasly all unsensitive in comom use Penicillin and cefohlosporins. The selection of antibiotics depend on drug sensitive experiment plus Bifido （bifid triple viable） and satisfactory results achieved. Conclusion Infant prolonged chronic enteritis caused by Klebsiellae pneumoniae express atypical clinical symptoms. Part of them belong to ESBLs producing bacteria. Unsensitive to general antibiotics, One must select sensitive antibiotics and adjust intestinal biologic circumstances.
出处
《基层医学论坛》
2006年第2期120-121,共2页
The Medical Forum
