摘要
目的:研究扇贝糖蛋白及扇贝多糖对S180小鼠的抑瘤作用。方法:给小鼠接种S180腹水瘤,用不同剂量扇贝糖蛋白及扇贝多糖治疗,观察瘤重及脾脏重量。结果:40 mg·kg-1扇贝糖蛋白对S180小鼠抑瘤率为47．29％,20 mg·kg-1扇贝多糖抑瘤率为46．97％;扇贝多糖还可明显增加小鼠脾脏重量。结论:扇贝糖蛋白及扇贝多糖抑瘤效果显著,扇贝多糖还具增强免疫功能作用。
Objective： To study the antitumor activity of Chlamysfarreri glycoprotein（FAGP） and polysaccharide（FPS） on S180 mice. Method： The mice were inoculated with S180, after treated with different doses of FAGP and FPS injection, the tumor and the spleen weight were observed. Result： FAGP＇s antitumor rate was 47.29%, and FPS＇was 46.97%, the best adaptable dose of FPS＇antitumor activity was 20 mg·kg^-1 ,only half of FAGP（40 mg·kg^-1）. Conclusion： The FAGP and FPS had salient antitumor activity, FPS can also improve the immunity activity.
出处
《中国药师》
CAS
2006年第2期123-124,共2页
China Pharmacist
关键词
扇贝
糖蛋白
多糖
抑瘤
Chlamysfarreri
Glycoprotein
Polysaccharide
Antitumor activity
