摘要
目的探讨佳苏伦对高海拔地区全麻催醒的作用及适宜剂量。方法40例择期行腹腔镜胆囊切除的病人,随机分为四组,每组10例。Ⅰ组(对照组)不用佳苏伦,Ⅱ、Ⅲ、Ⅳ组分别于关腹即刻静注佳苏伦0.5mg/kg、1mg/kg、2mg/kg。观察每组病人神志、自主呼吸恢复时间及气管拔管时间。结果与对照组比,Ⅱ组病人各指标无显著差别;Ⅲ、Ⅳ组病人神志、自主呼吸恢复快,气管拔管早;Ⅳ组病人又比Ⅲ组苏醒快,但生命征不及Ⅲ组稳定。结论佳苏伦能加速高海拔地区病人全麻后苏醒,适宜剂量为1mg/kg。
Objective To study the effect of hydrochloride doxapram in general anesthesia at high altitude and its appropriate dosage. Methods 40 patients underdoing laparoscope cholecystectomy were divided randomly into 4 groups （ n = 10） ,0.5 mg/kg, 1mg/kg,2mg/kg doxapram were given to Group Ⅱ ,Ⅲ, Ⅳ respectively immediately after operation while Group Ⅰ received no doxapram; the time of consciousness restoration, respiratory restoration and postoperative extubation were observed. Results The data of Group Ⅰ and Group Ⅱ were not significantly different （ P 〉 0.05 ） ; the time of consciousness restoration, respiratory restoration and postoperative extubation of Group Ⅲ and Ⅳ was shorter than those of Group Ⅰ and Ⅱ . Conclusions Doxapram is effective in general anesthesia and the appropriate dosage is 1mg/kg.
出处
《西南军医》
2006年第1期25-26,共2页
Journal of Military Surgeon in Southwest China
关键词
多沙普伦
高原
全麻
doxapram high altitude general anesthesia
