摘要
目的探讨胚胎体内注射生理盐水减胎的可行性。方法将2000年1月至2004年12月因2胎或2胎以上孕8-10周的多胎妊娠在广州市第二人民医院接受减胎的孕妇32例，分成两组，一组采用胚胎体内注射生理盐水减胎，为注射组；另一组采用机械破坏法减胎，为机械组。比较两组的手术时间、感染率、流产率、早产率、足月产率、平均孕周。结果两组病例均1次减胎手术成功。注射组减灭1个胎儿所需的时间为（5．8±1．8）min，非常显著地少于机械组的（18．6±10．2）min（P〈0．01）。注射组术后无感染发生，机械组有1例发生感染。注射组的流产率、早产率分别为5．6％（1／18）和27．8％（5／18），低于机械组的21．4％（3／14）和28．6％（4／14），但无统计学意义。注射组的足月产率为66．7％（12／18），高于机械组的50．0％（7／14），无统计学差异。注射组平均孕周为（35．2±3．6）周，显著长于机械组的（32．1±4．1）周（P〈0．05）。结论与机械破坏法比较，胚胎体内注射生理盐水是一种安全、有效、可行的减胎方法，适用于妊娠8—10周需要减胎的多胎妊娠孕妇。
Objective To evaluate the feasibility of fetus injected with saline in muhifetal pregnancy reduction. Methods From Jan. 2000 to Dec. 2004,32 cases with multiple pregnancy （8 - 10 weeks） were randomly divided into two groups in the Second People＇s Hospital of Guangzhou. There were 18 cases in group A, 14 cases in group B. The cases in group A underwent muhifetal pregnancy reduction with fetus injection of saline. Those cases in group B received muhifetal pregnancy reduction with needle puncture. The average operation time, infective rate, abortive rate, premature delivery rate, term delivery rate and the mean gestational age of the two groups were compared. Results Both groups achieved success. The average operation time of group A was （5.8 ± 1.8 ） rain, much lower than that of group B, which was （18.6 ± 10, 2）rain, （P 〈 0.001 ）. 1 case was infected in group B. No case was infected in group A. The abortive rate was 5.6% （1/18）in group A and 21.4% （3/14） in group B. 5 cases were premature delivery and 12 cases underwent term delivery in group A. 4 cases were premature delivery and 7 cases underwent term delivery in group B. The mean gestational age of group A were 35.2 ± 3.6, longer than that of group B（ 32.1 ± 4.1 ）, P 〈 0.05. Conclusion Fetus injection of saline at 8 - 10 gestatinal week is a safe method for muhifetal pregnancy reduction.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2006年第1期41-43,共3页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
多胎妊娠
胚胎减灭术
Multiple pregnancy
Mutifetal reduction
