摘要
目的:回顾分析12例240个正常肺段的磁共振肺灌注成像(magneticresonancepulmonaryperfusion,MRPP),初步探讨MRPP的方法及临床意义。方法:12例核素肺通气灌注扫描正常、无呼吸系统疾病及右心功能障碍的患者,分别进行增强磁共振肺动脉造影(magneticresonancepulmonaryangiography,MRPA)、MRPP检查。通过在MRPP显示的各肺段区域内设置感兴趣区,测量信号强度(signalintensity,SI)、时间—信号曲线,获取灌注高峰期信号强度变化率(transformationrateofsignal,TROS)。测量各部位TROS。结果:1·MRPP拥有较高的时间、空间分辨率,可以获得首次通过肺实质灌注高峰相,以显示肺循环血流变化。2·通过信号强度变化率半定量分析肺动脉血流,MRPP显示正常肺灌注信号均匀,TROS=227%±52·32%,3·时间—信号强度曲线显示肺动脉灌注高峰期时相,峰值时间为(9.83±1.19)s。结论:拥有高空间分辨率及时间分辨率的MRPP能够显示肺血流动力学的变化,有广阔的临床应用前景。
Objective：Review study 12 cases 240 normal pulmonary segments magnetic resonance pulmonary perfusion imaging, to have a pilot study in the method and the value of MRPP. Method： 12 cases that with normal nuclide pulmonary perfusion- ventilation scan, without respiratory system disease and right ventricular functional disorder were examined with MRPA and MRPP, Setting the area of interesting in pulmonary segment of lung field respectively, and detected signal intensity and time-signal curve to obtain the transformation rate of signal （TROS） during perfusion peak value. Result： 1. The MRPP has a higher spatial resolution and temporal resolution , though the first pass perfusion method , we can get the peak value of pulmonary parenehyma ; 2. Use the transformation rate of signal （TROS） quasi- ration measure the pulmonary flow, the signal intensity of normal pulmonary perfusion area is symmetrical, and TROS = 227% ＋ 52.32% . 3. Time-signal curve display the time of perfusion peak value is about 9.83 ＋ 1.19 second. Conclusion： A higher spatial resolution and temporal resolution of MRPP is a useful method in display pulmonary circular change. It has immensurable potential advantage.
出处
《心肺血管病杂志》
CAS
2005年第4期207-209,共3页
Journal of Cardiovascular and Pulmonary Diseases
关键词
磁共振波普学
磁共振肺灌注成像
核素肺通气灌注扫描
Magnetic resonance spectroscopy Magnetic resonance pulmonary perfusion Nuclide pulmonary perfusion-ventilation scans
