摘要
目的探讨腔隙性脑梗死(LI)患者的抑郁情绪和P300电位变化及其临床价值。方法对60例LI患者和59例健康者分别进行了P300电位测定和抑郁量表评定,并将2组结果加以比较。结果与对照组相比,LI组P300电位成分中N2、P3波潜伏期延长和P3波幅降低,其差异具有显著性(P<0.05或P<0.01)。抑郁量表评定各因子分2组相比存在显著性差异(P<0.01)。结论部分LI患者存在抑郁情绪和认知功能障碍,P300电位可作为评价其认知功能的指标应用于临床。
Objective To explore the clinical value of changes of depressive emotion and P300（EP） evoked potentials in patients with lacunar infarct （LI）. Methods Sixty LI patients and fifty-nine normal subjects were tested with P300 potentials and SDS, respectively, and the results were compared in two groups. Results Compared with control group, the latency of N2 and P3 of p300 potentials were longer and the amplitude of P3 were lower in LI group, there were significant dif- ference between the two groups（P 〈 0.05 or P 〈 0.01 ）. The scores of factas of SDS in the two groups had significant difference（P 〈 0.01）. Conclusion The LI patients exists depression and cognitive dysfunction. The P300 EP can be used for clinic as an index to cognltiveability in LI patients.
出处
《新乡医学院学报》
CAS
2006年第1期14-15,共2页
Journal of Xinxiang Medical University
基金
河南省高校青年骨干教师资助项目(No:2001162)
