摘要
目的总结近年来羊膜的基础及临床应用研究进展。方法广泛查阅国内外有关羊膜的基础和临床应用研究文献,总结其研究成果。结果羊膜来源广泛、价格便宜、对细胞相容性好、抗原性低,羊膜上皮层含有羊膜上皮细胞及多种生长因子,基底膜含有、、、、型胶原,纤维连接蛋白及糖蛋白,这些独特的结构使其对多种细胞生长有促进作用,羊膜已在眼科临床中得到广泛应用。结论使用羊膜不违背伦理,随着对羊膜的进一步深入研究,以及组织工程、生物工程对材料需求的进一步加大,其应用会更加广泛。
Objective To review the latest development of amniotic membrane and its application. Methods Related literatures on the development of amniotic membrane and its application were extensively reviewed and summarized. Results There were amniotic epithelial cells and many growth factors in the outer layer of amniotic membrane and there were many kinds of collagen in the basement. The special structure promoted the growth of many kinds of cells. It was widely used in ophthalmology. Conclusion As it is easily available, compatible, cheap in price, low in antigenicity, and able to promote the growth of many kinds of cells, with few ethical problems involved, amniotic membrane will be more and more widely applied.
出处
《中国修复重建外科杂志》
CAS
CSCD
北大核心
2006年第1期65-68,共4页
Chinese Journal of Reparative and Reconstructive Surgery
基金
国家高技术研究发展计划(863)资助项目(2001AA216011)
关键词
羊膜
应用
进展
Amniotic membrane Application Development
