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血管细胞粘附分子在风湿性疾病方面的研究 被引量:1

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摘要 血管细胞粘附分子-1(vascular cell adhesion molecule 1,VCAM-1)是一种重要的细胞粘附分子,属免疫球蛋白超家族(IGSF)成员,又称可溶性细胞粘附分子(INCAM),意指可在IL-1,TNF等细胞因子的作用后表达,分子量100 KDa或110 KDa,现命名CD106,与整合素家族的VLA-4(CD49d/CD29,α4β1)或α4β7结合,参与淋巴细胞的分化发育,在炎症、肿瘤转移、自身免疫性疾病、寄生虫感染等病理过程中也起重要的作用.
作者 傅卓 任少敏
出处 《中国基层医药》 CAS 2005年第11期1624-1625,共2页 Chinese Journal of Primary Medicine and Pharmacy
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