摘要
目的:前瞻性探讨C-erbB2表达等指标对肺腺癌的复发及生存期的影响。方法:采用免疫组化等方法检测70例肺腺癌的病理标本C-erbB2表达等,并长期随访患者。结果:患者的KPS评分、肿块大小、有无远处转移、TNM分期以及C-erbB2表达等与肺腺癌复发及生存期有关(P<0.05)。结论:患者的KPS评分、肿块大小、有无淋巴结转移、TNM分期以及C-erbB2表达等指标可以预测肺腺癌的预后。
Objective This article is a prospective study on the prognostic significance of over - expression of C - erbB2 as well as several clinical data in patients with adenocarcinoma of lung. Methods C -erbB2 expressions were determined with immunohisto chemistry in the pathologic specimens of 70 patients with adenocarcinoma of lung. Those patients were regularly followed after operation （ until lost or death）. Results Over expression of C - erbB2 predicted sbortened survival and was significantly related to the survival period or TFP after operation in the patients with adenocarcinoma of lung （ P 〈 0.05 ）. The same was true with KPS score 〈 70, larger tumor mass （ 〉 3cm）, presence of local or distant metastasis as well as late TMN stage. Conclusion Over expression of C - erbB2 predicts less favorable outcomes after operation in patients with adenocarcinoma of lung.
出处
《放射免疫学杂志》
CAS
2005年第6期507-509,共3页
Journal of Radioimmanology
