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单侧骨皮质缺损对长管状骨生物力学的影响 被引量:8

An experimental study on biomechanical effects due to unilateral cortical bone defect in long tubular bone
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摘要 目的探讨长管状骨骨干不同大小的单侧骨皮质缺损对长管状骨生物力学性质的影响。方法取76根三黄鸡胫骨,随机分7组(1.5mm组n=11,2.0mm组n=9,2.5mm组n=13,3.0mm组n=12,3.5mm组n=8,4.5mm组n=11,皮质完整组即正常对照组n=12),于后侧骨皮质造成直径分别为1.5~4.5mm的环形骨缺损,进行三点弯曲单一实验,皮质完整组作为正常组对照。结果缺损直径为1.5mm及2.0mm组鸡胫骨达到结构破坏时的最大载荷与正常组差异无统计学意义(P=0.824,0.865),2.5mm、3.0mm、3.5mm组的最大载荷较正常组降低14%左右,差异有统计学意义(P=0.015,0.010,0.021);4.5mm组较正常组降低23%左右,差异有统计学意义(P=0.001)。结论单侧皮质缺损直径在长管状骨外径的(22.6±1.4)%以内时,不影响其抗弯曲性能;当其超过长管状骨外径的(29.4±2.1)%时,将降低长管状骨的抗弯曲性能,但降低的幅度跟缺损大小并不完全呈正比。 Objective To investigate the biomechanics effect due to unilateral cortical bone defect of different size in long tubular bone. Methods Seventy-six pieces of Sanhuang cock tibial were randomly divided into 7 groups. The unilateral diaphsis cortical were drilled holes of different size, include 1.5,2.0, 2. 5, 3.0, 3.5, and 4. 5 mm, performed three-points bend single experiment. The intact bone cortical group was control group. Results When there were bone structure distructions, the maximum of the bend load between 3 groups which bone defect diameter were 1.5 mm, 2.0 nun, and controll was not significant difference ( P=0. 824, 0. 865 ), but the maximum of the bend load between 3 groups which bone defect diameter were 2. 5, 3.0, and 3.5 mm decreasing about 14 percent of the control group(P=0. 015, 0. 010, 0. 021 ). and the maximum of the bend load which bone defect diameter were 4. 5 nun decrease about 23 percent of the controll group ( P=0. 001 ). Conclusions If the diameter of bone cortical defect is within 22. 63±1.39 percent of bone cortical outer diameter, there was no reduction of the bend load. If the diameter of bone cortical defect is beyond 29. 36±2.07 percent of bone cortical outer diameter, it decreases the maximum bend load of the long tubular bone, but the reduced range is not complete with direct ratio to the bone defect size.
出处 《中华外科杂志》 CAS CSCD 北大核心 2005年第24期1602-1604,共3页 Chinese Journal of Surgery
关键词 生物力学 骨干 骨缺损 长管状骨 Biomechanics Diaphyses Bone defect Long tubular bone
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参考文献4

  • 1Edgerton BC,An KN,Morrey BF.Torsional strength reduction due to cortical defects in bone.J Orthop Res,1990,8:851-855.
  • 2Hipp JA,Edgerton BC,An KN,et al.Structural consequence of transcortical holes in long bones loaded in torsion.J Biomech,1990,23:1261-1268.
  • 3Kuo RF,Chao EY,Rim K,et al.The effect of defect size on the stress concentration and fracture characteristics for a tubular torsional model with a transverse hole.J Biomech,1991,24:147-155.
  • 4Elias JJ,Frassica FJ,Chao EY.The open section effect in a long bone with a longitudinal defect-a theoretical modeling study.J Biomech,2000,33:1517-1522.

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