摘要
目的探讨老年高血压时肾脏受损情况。方法采用放射免疫分析法对７７例老年高血压患者进行血、尿β２微球蛋白（β２－ＭＧ）、糖蛋白（ＴＨＰ）及尿白蛋白（Ａｌｂ）的检测，并以３０例健康老人作为对照。结果患者血、尿β２－ＭＧ与尿Ａｌｂ含量均明显高于对照组（Ｐ＜０．０１）。随病程延长，β２－ＭＧ与Ａｌｂ增高愈明显。血、尿ＴＨＰ较正常组降低（Ｐ＜０．０５）。结论血、尿β２－ＭＧ、ＴＨＰ及尿Ａｌｂ的检测是用于判断肾脏功能早期病变的一项重要指标，对于判断肾小球或肾小管的损害程度。
Aim\ To investigate the changes of serum and urine excretion of β 2 MG, Tamm Horsfall protien(THP) and albumin(Alb) elderly hypertensive patients.\ Methods\ β 2 MG, THP and Alb were measured in fifty patients and twenty seven hypertension complicated with diabetes using radioimmunoassay(RIA), and thirty healthy elderly persons served as controls.\ Results\ The serum and urine of β 2 MG and Alb were obviously increased in patients with hypertension, however the TMP content were decreased both in serum and urine. These changes could be detected earlier than the change serum creatinine(Cr) and blood urea nitrogen(BUN) were shown. If the course of hypertension was longer than 10 year, Cr and BUN usually increased as well.\ Conclusion\ Clinical determination of β 2 MG, THP and Alb in elderly hypertension may possess an early diagnostic value for revealing the damage of renal function.
出处
《高血压杂志》
CSCD
1996年第3期228-230,共3页
Chinese Journal of Hypertension
关键词
微球蛋白
白蛋白
高血压
老年人
糖蛋白
β 2 MG\ Tamm Horsfall protien\ albumin\ elderly hypertension
