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外伤性癫痫病人脑脊液中离子钙含量变化初步研究 被引量:2

The elemental research on the content of the ionic calcium in cerebrospinal fluid of thepatient with traumatic epilepsy
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摘要 应用ILEX临床电解质分析仪检测了30例脑外伤后癫痫病人脑脊液中离子钙(Ca2+)含量变化。结果:癫痫发作后3小时脑脊液中Ca2+含量明显低于对照组(P<0.01),发作间歇期Ca2+含量回升,二次发作时再度降低。表明癫痫发作期间病人脑脊液中Ca2+含量水平下降,同时预示大量Ca2+进入细胞内。在抗癫痫治疗同时加用Ca2+拮抗剂,有益于继发性脑损伤的防治。 o analysis the changes of the content ofionic calcium(C22+),we tested the cerebrospinal fluid(CSF)of 30 patients with post traumatic epilepsy using the ILEX chinic electrolyte analyer. We observed thatthe content of Ca ̄2+ in CSF of the patient was significantly lower than that of the controls at 3 hours afterthe epilepsy,then it increased,and when the epilepsy appeared again,it decreased.This study suggestedthat the content of Ca ̄2+ in CSF of the patient decreased and C ̄2+ flowed into the cells at the time ofepilepsy. On the basis of these findings,we consider that the Ca ̄2+ -inhibitors may play a major role inthe prevention and treatment of the secondary brain injury when the anti-epilepsy medicine is used atthe same time
出处 《功能性和立体定向神经外科杂志》 1996年第2期13-15,共3页
关键词 颅脑损伤 外伤性 癫痫 脑脊液 钙离子 Brain injury Epilepsy Ionic calcium in cerebrospinal fluid
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  • 1团体著者,实用神经病学,1978年
  • 2徐如祥,中华神经外科杂志,1992年,8卷,105页
  • 3徐如祥,中华神经外科杂志,1992年,8卷,41页
  • 4徐如祥,Chinese Medical Journal,1991年,104卷,634页
  • 5文允镒,生理科学,1988年,8卷,489页
  • 6张均田,中国药理学报,1987年,3卷,235页

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