摘要
应用ILEX临床电解质分析仪检测了30例脑外伤后癫痫病人脑脊液中离子钙(Ca2+)含量变化。结果:癫痫发作后3小时脑脊液中Ca2+含量明显低于对照组(P<0.01),发作间歇期Ca2+含量回升,二次发作时再度降低。表明癫痫发作期间病人脑脊液中Ca2+含量水平下降,同时预示大量Ca2+进入细胞内。在抗癫痫治疗同时加用Ca2+拮抗剂,有益于继发性脑损伤的防治。
o analysis the changes of the content ofionic calcium(C22+),we tested the cerebrospinal fluid(CSF)of 30 patients with post traumatic epilepsy using the ILEX chinic electrolyte analyer. We observed thatthe content of Ca ̄2+ in CSF of the patient was significantly lower than that of the controls at 3 hours afterthe epilepsy,then it increased,and when the epilepsy appeared again,it decreased.This study suggestedthat the content of Ca ̄2+ in CSF of the patient decreased and C ̄2+ flowed into the cells at the time ofepilepsy. On the basis of these findings,we consider that the Ca ̄2+ -inhibitors may play a major role inthe prevention and treatment of the secondary brain injury when the anti-epilepsy medicine is used atthe same time
关键词
颅脑损伤
外伤性
癫痫
脑脊液
钙离子
Brain injury
Epilepsy
Ionic calcium in cerebrospinal fluid