摘要
90例新生儿应激性溃疡病例随机分成2组,治疗组44例,对照组46例。两组胎龄、出生日龄、基础疾病及治疗、病程基本一致。治疗组静滴西咪替丁10mg/kg,bid,3d;对照组给予Vit K_1和酚磺乙酚。治疗组总有效率和显效率为88.6％和59.1％,对照组为65.2％和26.1％,两组间,差别具有统计学意义(P<0.05和P<0.01)。结论:西咪替丁治疗新生儿应激性溃疡效果肯定,也未发现明显毒副作用。
Ninety cases of neonate stress ulcer were divided into two groups at random, including treatment group (44 cases) and control group (46 cases). The patients in two groups were controlled for conceptus age, age, underlying diseases, treatment and disease course. The treatment group was given cimetidine (10mg/kg, bid) and control group was treated by Vit K| and dicynomum. The total effective rate and effective rate in treatment group were 88. 6% and 59. 1% while the total effective rate and effective rate in control group were 65. 2% and 26. 1%. Our results showed that cimetidine was effective for the treatment of neonate stress ulcer, with no obvious adverse effects found.
出处
《药物流行病学杂志》
CAS
1996年第3期133-134,共2页
Chinese Journal of Pharmacoepidemiology
