摘要
目的观察疏血通注射液(其主要成分为水蛭素)对原发性脑出血血肿吸收、血肿周围低密度区改变和神经功能恢复的影响。方法465例原发性脑出血患者随机分为治疗组和对照组。治疗组给予疏血通注射液6mL,1次/d静滴,连用21d,甘露醇作为基础治疗药物。于治疗第4、10和第21天行CT检查测量血肿体积、血肿周围低密度区改变,肢体功能改变采用欧洲卒中量表(ESS)进行评价。结果与对照组相比,第10和21天治疗组血肿体积和血肿周围低密度区明显缩小(P<0·01),ESS评分较高(P<0·05)。结论疏血通注射液能促进脑出血时的血肿吸收、血肿周围低密度区缩小和神经功能改善。
Objective： To observe the effect of Chinese medicine injection. Its main composition Shuxuetong injection （a kind of traditional is hirudin） on the absorption of hematoma during primary intracerebral hemorrhage, the changes of low-density areas surrotmding hemato- mas and the recovery of neurological function. Methods： Of the 465 patients with primary intracerebral hemorrhage were randomly divided into a treatment group and a control group. The treatment group received Shuxuetong injection 6 mL intravenously once a day for 21 days. Mannitol was used as the basic medication. CT was used to evaluate the volumes of hematomas, the changes of low-density areas surrounding hematomas at day 4, 10 and 21 after the treatment, and the changes of limb function were evaluated using the European stroke scale （ESS）. Results： Compared with the control group, the volumes of hematomas and the low density areas surrounding hematomas reduced significantly in the treatment group （P 〈 0.01 ）, and ESS is higher （P 〈0.05） at day 10 and 21. Conclusion： Shuxuetong injection can promote the absorption of hematoma, reduce the low-density areas surrounding hematomas and improve the neurological function during intracerebral hemorrhage.
出处
《国外医学（脑血管疾病分册）》
2005年第10期744-746,共3页
Foreign Medical Sciences Cerebrovascular Diseases
