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新生儿呼吸机相关性肺炎病原学分析 被引量:2

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摘要 [目的]探讨新生儿监护病房(NICU)中呼吸机相关性肺炎(ventilator-associated pneumonia,VAP)的发病情况、病原菌组成及其耐药性,为临床治疗提供依据.[方法]对陕西省妇幼保健院NICU中2002年10月~2004年7月的30例VAP患儿进行病原学分析.[结果]机械通气方式、通气时间与VAP发病有关;病原菌组成前4位主要是溶血性葡萄球菌,肺炎克雷氏杆菌,凝固酶阴性葡萄球菌,铜绿假单胞菌.革兰氏阳性球菌对青霉素,氨苄青霉素,第三代头孢菌素基本耐药,对万古霉素敏感;革兰氏阴性杆菌对常用第三代头孢菌素全部耐药,对氨基糖甙类、喹喏酮类部分敏感.[结论]防治VAP的关键是尽量选用损伤小的通气方式,缩短通气时间,避免滥用/过度使用抗生素尤其是第三代头孢菌素,减少耐药菌株产生.
作者 郭金珍 张娟
出处 《中国儿童保健杂志》 CAS 2005年第6期547-549,共3页 Chinese Journal of Child Health Care
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参考文献5

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二级参考文献21

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