摘要
目的:评价文拉法辛与帕罗西汀治疗焦虑症的疗效和不良反应。方法:将符合中国精神障碍分类与诊断标准第3版诊断标准的52例门诊或住院抑郁症患者,随机平分为两组,分别给予文拉法辛和帕罗西汀治疗,疗程6周。用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、临床疗效总评量表的病情严重程度(CG I-S1)和副反应量表(TESS)评定疗效和不良反应。结果:文拉法辛与帕罗西汀对抑郁症疗效接近,但前者起效更快,不良反应少于后者。结论:文拉法新是一种安全、有效的新一代抗抑郁药,可以作为治疗抑郁症的第一线用药。
Objective：To compare with efficacy and side effects between venlafaxine and paroxetine in the treatment of depression. Methods：52 inpatients and outpatients with a diagnosis of depression according to the CCMD -3 criteria were involved in this study; they were randomly divided into the venlafaxine group （ n = 26） and the paroxetine group （ n = 26） for 6 weeks. Effects and side effects were evaluated with HAMD, HAMA, CGI -SI and TESS before and after the treatment. Results： Findings indicated that efficacy of venlafaxine was the similar to those of paroxetine. However, venlafaxine took effect more quickly and its side effects were less than paroxetine. Conclusions ：Venlafaxine is an effective and safe antidepressant. It is suggested that venlafaxine could he used as a first - line antidepressant in the treatment of depression for the elder.
出处
《中国民康医学》
2005年第12期723-724,727,共3页
Medical Journal of Chinese People’s Health
