摘要
目的建立厚朴饮片(厚朴、姜厚朴)的质量控制标准.方法测定4个产地各10个批次的厚朴和姜厚朴饮片的水分、总灰分、酸不溶性灰分、醇溶性浸出物及其有效成分厚朴酚与和厚朴酚的含量,并进行显微鉴别和薄层鉴别,在此基础上建立各指标的质量控制标准.结果测得了厚朴和姜厚朴饮片各指标含量平均值,其中水分分别为8.31%,8.47%;总灰分分别为3.77%,3.79%;酸不溶性灰分分别为1.58%,1.89%;70%乙醇溶液浸出物分别为20.67%,21.55%;厚朴酚与和厚朴酚总量分别为4.34%,3.62%.结论建议厚朴和姜厚朴饮片的质量标准暂定为:水分7%～13%,总灰分不得高于5.0%,酸不溶性灰分不得高于3.0%,70%乙醇溶液浸出物不得低于18.0%,厚朴酚与和厚朴酚含量之和分别不得低于2.5%,2.0%.
Objective To build up quality standards for medicinal magnolia bark （raw slices of the bark and slices stir-baked with ginger juice）. Methods The contents of moisture, total ash, acid-insoluble ash, ethanol soluble extract and its active principles magnolol and honokiol of 10 batches of medicinal magnolia bark from 4 different growing areas were determined and submitted to mieromanipulation and TLC identification. On the basis of these examinations, the quality standards of all the indices were built up. Results The average values of the indices of the raw slices and slices stir-baked with ginger juice of the drug were ： moisture 8.31%/8.47%, total ash 3.77%/3.79%, acid-insoluble ash 1.58%/1.89%, 70% ethanol extract 20.67%/21.55% , the sum total of magnolol and honokiol 4.34%/3.62%, respectively. Conclusion It is suggested by the authors of the present study that the quality standards of medicinal magnolia bark （ raw slices and slices stir-baked with ginger juice） could be tentatively arranged as follows： moisture, 7% - 13% ; total ash, not more than 5.0%, acid-insoluble ash, not more than 3.0%; 70% ethanol extract, no less than 18.0%, the sum total of magnolol and honokiol ,no less than 2.5%/2.0%, respectively.
出处
《医药导报》
CAS
2005年第12期1154-1156,共3页
Herald of Medicine
关键词
厚朴
姜厚朴
质量标准
Raw slices of Medicinal Magnolia Bark
Medicinal Magnolia Bark slices stir-baked with ginger juice
Quality standard
