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成人继发孔型房间隔缺损的介入治疗 被引量:2

Transcatheter closure of secondary atrial septal defects in adult patients
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摘要 目的:评价成人继发孔型房间缺损(ASD) 治疗的效果.方法:45例术前超声心动图检查ASD最大直径8~38(27±7)mm,5例为多孔型房间隔缺损.所有病例均经导管置入1个Amplatzer ASD封堵器(ASO).术后24h、1个月、3个月、6个月、1年及并每年1次分别行经胸超声心动图(TTE)、心电图及X线检查.结果:41例封堵成功,选择的ASO直径为10~40(31±7)mm,ASO/ASD直径比值平均为1.15:1.3例ASD最大直径分别为20mm、24mm和26mm,在封堵器无法与房间隔平行而封堵失败.1例ASD最大直径为38mm,选用40mm的ASO,封堵器脱落至右房,急诊手术.术后即刻TTE显示33例存在微量至少量残余分流,术后24h 2例存在微量残余分流,术后3月仅1例有微量残余分流.术后右心房、室稍缩小,心功能明显改善.结论:成人继发孔型ASD的介入治疗安全、有效,并发症少. Objective:To evaluate the therapeutic efficacy of transcather closure of atrial septal defect (ASD) in adult patients using Amplatzer ecduder device. Methods:There were 45 patients. The age was 49 ± 7 years (ranging from 40 to 65 years).The diameter of ASD was 27 ±7mm (ranging from 8 to 38mm) shown by echocardiography before the interventions. Two cases had double ASD. There were 29 patients with tricuspid regurgitation, 8 with mitral valve regurgitation, 3 with atrial fibrillation,and 7 with atrial premature beats. Each case was occluded using Amplatzer oceluder device through the pereutaneous procedure. Eehocardiography was performed immediate- ly, and echocardiography, ECG and X-ray examination were perforomed at 24h, 1,3,6 months and each year after the procedure to evaluate the efficacy. Results : The diameter of the eceluder selected was 31 ± 7mm (ranging from 10 ~ 40)mm. 41 eases were occluded successfully.Trivial to small residual shunts were found in 33 cases immediately after the procedure,in 2 eases after 24h and 1 case 3 month after the procedure. Echocardiography and X-ray examination showed that heart size were improved. Conclusion:Transcatheter closure of secondary ASD in adult is safe and efficacious.
出处 《医学影像学杂志》 2005年第11期933-935,共3页 Journal of Medical Imaging
基金 山东省科技厅立项课题(2001BB1DBA2)
关键词 房间隔缺损 介入治疗 成人 Atrial septal defect Therapy, interventional Adult
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参考文献7

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  • 2Fischer G, Stieh J, Uebing A, et al. Experience with transcatheter closure of secundum atrial septal defects using the Amplatzer septal occluder: a single centre study in 236 consecutive patients[J]. Heart,2003,89:199-204.
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二级参考文献10

  • 1King TD,Mills Nl. Nonoperative closure of artrial septal defects[J]. Surgery, 1974,75:383-388.
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