摘要
目的观察全程督导短程间歇化疗方案治疗涂阳肺结核的疗效。方法对１２５例初治和２４９例复治涂阳肺结核患者，分别采用２Ｈ３Ｒ３Ｚ３Ｓ３（Ｅ３）／４Ｈ３Ｒ３（异烟肼：Ｈ，利福平：Ｒ，吡嗪酰胺：Ｅ，链霉素：Ｓ，乙胺丁醇：Ｅ）和２Ｈ３Ｒ３Ｚ３Ｓ３Ｅ３／６Ｈ３Ｒ３Ｅ３化疗方案，实施全程督导化疗、管理。结果总完成治疗率为９９．７％；初、复治患者满疗程痰菌转阴率分别为９６．７％和８４．８％；经３年随访，细菌学复发率初治患者为１．８％，复治患者为１０．２％。结论全程督导短程间歇化疗方案对控制结核病具有简便、经济和高效的实用价值。
ObjectiveToevaluatetheefectsofintermitentshort-coursechemotherapyunderful-coursesuper-visiononthetreatmentofsmearpositivepulmonarytuberculosis.MethodTheregimensof2H3R3Z3S3(E3)/4H3R3and2H3R3Z3S3E3/6H3R3E3wererespectivelyusedin125initialand249relapsesmearpositivepulmonarytubercu-losiscasesunderful-coursesupervisionandmanagement.ResultsThetotalrateoftreatmentcompletionwas99.7%,andtheratesofsputumnegativeconversioninini-tialandrelapsecaseswere96.7%and84.8%respectively.Duringthree-yearfolow-up,thebacterio-logicalrelapserateswerefoundtobe1.8%ininitialcasesand10.2%inrelapsecases.ConclusionsTheregimenwasprovedtobeconvenient,economicalandefectiveintuberculosiscon-trolprogramme.
出处
《中华结核和呼吸杂志》
CAS
CSCD
北大核心
1996年第2期104-106,共3页
Chinese Journal of Tuberculosis and Respiratory Diseases
关键词
肺结核
综合疗法
药物疗法
Tuberculosis,pulmonaryCombinedmedalitytherapy
