摘要
目的:用正畸学方法建立个别后牙移动的动物模型,观察其对大鼠咀嚼肌机械疼痛阈值的影响.方法:①个别后牙移动:采用Waldo方法--将一正畸皮圈(3M Unitek,1/8#)插入26、27之间,以27、28为支抗向近中推26.②痛觉测量:参照Ren所报道方法,据von Frey尼龙毛粗细和动物痛觉反应次数,确定咬肌疼痛分值.③用游标卡尺测量鼠26移动距离.结果:①26在1周内移动到最大距离0.8 mm.②在3～9 d双侧颞肌表现出痛觉敏感,疼痛高峰出现在第5～7天,双侧之间没有明显区别(P＞0.05),右侧(对照侧)略高于左侧(实验侧).③咬肌与颞肌的变化类似,疼痛峰值也出现在第7天,持续约12 d左右,左侧比右侧稍高,并在第7天左侧(实验侧)明显高于右侧(对照侧)(P＜0.05).结论:个别后牙移动可以导致咬肌和颞肌痛觉敏感.
AIM ：To set up the animal model of masticatory muscle mechanical hyperalgesia induced by experimental tooth movement. METHODS：①lndividual tooth nlovement： An elastic rubber（3M Unitek, 1/8^#） was inserted between the first and second upper molars of Sprague - Dawley rat. ②Mechanical nocieeptive threshold measurement was done according to Ren＇s method, yon Frev filaments were used to assess the muscle mechanical threshold. ③ Sliding caliper was used to measure the distance between the first and second molars. RESULTS：①The first molar moved with maximum distance of 0.8 mm within one week. ②Bilateral temporal muscles showed hyperalgesia from 3rd to 9th day,and the peak time was 5 ～7th day. ③Masseter muscles were similar to the temporal muscles, and was induced hyperalgesia nearly from 3rd to 9th day,and the peak time was 7th day. CONCLUSION：Individual tooth movemcnt may lead to mastieatorv museles hyperalgesia.
出处
《牙体牙髓牙周病学杂志》
CAS
2005年第10期542-545,共4页
Chinese Journal of Conservative Dentistry
基金
国家自然科学基金资助项目(30471909)
关键词
牙齿移动
咀嚼肌
痛觉敏感
tooth movement
masticatory muscle
hyperalgesia
