摘要
目的 :探讨影像学检查及来源于胃肠道的转移性肝癌其肿瘤标志物的检测对转移性肝癌的诊断价值。方法 :采用回顾性分析的方法对我院近 7年来收治的 2 0 8例转移性肝癌患者行B超、CT等影像学检查 ,对来源于胃肠道的 12 1例转移性肝癌患者的癌胚抗原 (CEA)、甲胎蛋白 (AFP)等肿瘤标志物检测情况进行分析 ,以病理学检查结果作为诊断转移性肝癌的金标准 ,比较四种检查对诊断转移性肝癌的灵敏度 ,为诊断筛选方案的确定提供依据。结果 :CEA诊断的灵敏度为 71 4 %(6 0 / 84 ) ,AFP为 17 3%(13/ 75 ) ,B超为 79 1%(12 9/ 16 3) ,CT为89 6 %(95 / 10 6 )。经比较 ,CEA诊断胃肠道肿瘤肝转移的灵敏度高于AFP (P <0 0 5 ) ;CT高于B超 (P <0 0 5 )。结论 :CEA是诊断消化道肿瘤肝转移的一个较好指标 ,AFP诊断的意义不大。对B超检查阳性者做CT检查可提高其诊断的准确率 ,B超检查阴性者需作CT以提高转移性肝癌的检出率。
Objective： To analysis the efficacy of diagnosis froln imaging deteetion and tumor markers in metastatic liver cancer- originated from gastrointestinal tract. Method： B ultrasonography and Computer tomography （CT） were conducted in 208 eases hospitalized with metastatic liver cancer during revent seven years. Carcinoembryonic antigen （CEA） and Alpha - fetoprotein （AFP） were given in 121 patients with metastatic liver cancer. Pathologie diagalosis was regarded as the golden standard of diagnosing, their sensitivity was analvzed respectively. Result： Sensitivities of CEA, AFP, B ultrasonography and CT were 71.4% （60/84）, 17.3% （13/75）, 79.1% （129/163） and 89.6% （95/106）, respectively, Sensitivity of CEA was higher than that of AFP （ P 〈 0.05）, CT was higher than B ultrasonography （ P 〈 0.05）. Cunclusion： CEA was an important marker in diagnosing the metastatic liver cancer originated from gastrointestinal tract, AFP wasn＇t significant. CT was a better method in diagnosing metastatic liver cancer as compared with B ultrasonography.
出处
《华西医学》
CAS
2005年第1期22-23,共2页
West China Medical Journal
关键词
转移性肝癌
肿瘤标志物
影像学诊断
metastatic liver cancer
tumor markers
imaging diagnosis
