摘要
目的:研究胃炎患者血清幽门螺杆菌分类抗体免疫印迹检测的临床意义。方法:用14C呼气试验检测幽门螺杆菌感染;用免疫印迹法检测幽门螺杆菌分类抗体。结果:152例临床各型胃炎患者中,140人14C-呼气试验阳性(92.11%)。14C-呼气试验阳性组Hp分类抗体中CagA、VacA双阳性或单项阳性者127人(90.71%);阳性预测值90.7%,阴性预测值9.3%。结论:14C-呼气试验与幽门螺杆菌分类抗体两种方法组合检测,对临床幽门螺杆菌的诊断与治疗有重要作用;免疫印迹法检测幽门螺杆菌分类抗体,有简便、敏感、特异、快速的优点。
Objective：To study the clinical significance of detecting the classified antibodies of hehcobacter pylori （Hp） in the serum of gastritis patients by i mmuno-blot method.Methods：The infection of HP and classified antibodies （CagA and VacA） coming from the gastritis patients were iespectively detected by ^14C-UBT or immuno-blot method.Results：One hundred and forty of 153 patients with various forms of gastritis were positive in ^14C-UBT （92.11%）,among them 127 cases,whose classified antibodies （CagA and VacA） wre one or two positive,were found im immuno-blot method （90.71%）;The positive predictive value was 90.7%,and the negative predictive value was 9.3%.Conclusion：^14C-UBT combined with immuno-blot method is very important for the diagnosis and treatment of the infection of Hp.It is simple,sensitive,special and speedy to detect the classified antibodies of HP by immuno-blot method.
出处
《现代医药卫生》
2005年第23期3214-3215,共2页
Journal of Modern Medicine & Health
