摘要
背景与目的肺切除术是治疗非小细胞肺癌的首选方法之一,术后并发症是影响手术疗效的重要原因。本研究的目的是探讨非小细胞肺癌术后并发症的发生情况及改良的心肺危险指数(CPRI)在预计术后心肺并发症中的价值。方法选择2004年1月至2004年11月天津市肿瘤医院胸外科行肺切除的非小细胞肺癌患者,分析其并发症,并探讨改良的EpsteinCPRI在预计肺切除手术风险中的价值。结果全组256例患者中86例出现心肺并发症(33.6%),血胸6例(2.3%),其它并发症11例(4.3%)。按CPRI分级,CPRI≥4级者67例,其中61例出现心肺并发症,显著高于CPRI<4级组(P<0.05)。以CPRI≥4级为标准,预计肺切除手术风险的敏感性为70.9%,特异性为96.5%,准确率为87.9%。结论肺癌术后近期并发症主要为心肺并发症,CPRI在估计术后并发症方面有重要价值。
Background and objective Pulmonectomy is the first priority in treatment of non-small cell lung cancer （NSCLC）. The postoperative complication is the main factor which affects the efficacy of operation. The aim of this study is to analyze the incidences of postoperative complications in NSCLC patients and the value of modified cardiopulmonary risk index （CPRI） in predicting the short term complication. Methods Postoperative complications were analyzed in patients who underwent pulmonectomy in Tianjin Cancer Institute and Hospital from January 2004 to November 2004, and the value of modified Epstein CPRI in predicting the risk of pulmonectomy was estimated. Results A total of 256 consecutive patients were studied. Postoperative cardiopulmonary complications occurred in 86 patients （33.6%）, hemathorax in 6 patients （2.3%） and other complications in 11 patients （4.3 %）. Postoperative cardiopulmonary complications occurred in 61 of the 67 patients with CPRI≥4, which was significantly more frequent than that in those with CPRI〈4 （P〈0. 05）. Using CPRI≥4 as a threshold for predicting postoperative complication, the sensitivity, specificity and accuracy were 70.9%, 96. 5% and 87.9% respectively. Conclusion The main early postoperative complications are cardiopulmonary complications. CPRI shows significant importance in predicting the early postoperative prognosis for patients with NSCLC.
出处
《中国肺癌杂志》
CAS
2005年第5期462-464,共3页
Chinese Journal of Lung Cancer
关键词
非小细胞肺癌
心肺危险指数
并发症
Non-small cell lung cancer Cardiopulmonary risk index, CPRI Complication
