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经颈静脉途径肝内门体分流术(TIPS)治疗门脉高压食管静脉血张出血的临床评估 被引量:10

Clinical evaluation of trans-jugular intrahepatic portosystemic shunt(TIPs)inpatients with portal hypertensive variceal bleeding.
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摘要 TIPS术治疗50例,其中49例为肝炎后肝硬化,1例为门静脉海绵窦样变,45例有反复呕血及黑便史,5例无上消化道出血史,均有中-重度食管静脉曲张。16例有中-大量腹水。结果:(1)45例门静脉建立有效分流,成功率为90%。门静脉主干压力从术前的3.95±0.85kPa降至2.33±0.72kPa(P<0.001)。(2)胃镜检查TIPS术后食管静脉曲张消失和基本消失率为41.43%,减轻为37.9%。(3)术后腹水消失或减轻为62%。(4)并发症与操作有关的为12%,总发生率为36%。(5)术后肝功能观察:血清总胆红质升高,血清白蛋白降低。随访1993年3月至1994年3月置入Gianturc-RoschZ型、网型支架的24例患者,随访3个月至22个月者20例,支架狭窄、闭塞率半年为20%,1年为55%;复发出血8例为40%。1994年4月至1995年1月置入wallstent支架的21例中,尚无支架闭塞及反复出血。全组现共死亡8例,死亡率为15.6% Among 50 patients heald with TIP8,49 were posthepatitis cirrhosis onecavernous transformation of portal vein,45 of them had history of repeatedhematemesis and melena 5 had no history of upper gastrointestinal bleeding,but withmoderate to severe varices.16 had moderate to massive ascites,According to child’sclassification,31 patients were in class A,13 in class B and 6 in class C. The resultswere as follows:1.The portal venous shunts were successfully set up in 45 patients,thesuccessful rate was 90%,the presssure of portal venous trunk dropped from 3.95± 0.85kPa to 2.33 ± 0.72kPa (P< 0.001);2.The gastroscopy showed disappearance of varices in41.4%,reduction in caliter in 37.9%the total effective rate was 79.3%:Ascitesdisappeared the total rate of or decreased in 62%;4.Complication relaterd to manuveurwas l2%,the total rate of complication was 36%,Eight patients died due to rebleedingor hepatic failure during a of follow-up period, of 3~22 months
出处 《中华消化杂志》 CAS CSCD 北大核心 1996年第1期26-28,共3页 Chinese Journal of Digestion
关键词 分流术 出血 门脉高血压 治疗 TIPS Portal hypertensionTrannsjugular intrahepatic portosystemicshunt(TIPS)
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  • 1张金山,中华医学杂志,1994年,74卷,150页

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