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生精细胞凋亡的基因调控 被引量：21

Regulation of Spermatogenic Cells Apoptosis by Genes
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摘要 睾丸生精细胞凋亡是维持精子发生动态平衡,限制生精上皮生精细胞数量的一个重要生理机制,受多种因素调控。本文就基因等对精子发生过程中生精细胞凋亡调控的研究近况进行综述。 Apoptosis of spermatogenic cells is an important physiological mechanism that keeps spermatogenesis homeostatic and restricts germ cells amount in seminiferous epithelium and is regulated and controlled by multi-factors. This article summarized recent studies on regulation of cells apoptosis by hormone, genes and various physical and chemical factors in spermatogenesis.
作者 黄宇烽
机构地区 南京军区南京总医院生殖遗传研究室
出处 《中华男科学杂志》 CAS CSCD 2005年第9期643-646,共4页 National Journal of Andrology
关键词 生精细胞 凋亡 摹因 调控 激素 spermatogenic cells apoptosis gene regulation hormone
分类号 Q954.434 [生物学—动物学]
  • 相关文献

参考文献10

  • 1Vigier M, Weiss M, Perrard MH, et al. The effects of FSH and of testosterone on the completion of meiosis and the very early steps of spermiogenesis of the rat: an in vitro study[J]. J Mol Endocrinol, 2004, 33(3):729-742.
  • 2Lei ZM, Mishra S, Ponnuru P, et al. Testicular phenotype in luteinizing hormone receptor knockout animals and the effect of testosterone replacement therapy[J]. Biol Reprod, 2004, 71(5):1605-1613.
  • 3崔毓桂,陈子庆,沙家豪.激素对精子发生的调控[J].中华男科学杂志,2004,10(6):465-467. 被引量：28
  • 4Gancarczyk M, Paziewska-Hejmej A, Carreau S, et al. Dose-and photoperiod-dependent effects of 17beta-estradiol and the anti-estrogen ICI 182,780 on testicular structure, acceleration of spermatogenesis, and aromatase immunoexpression in immature bank voles[J]. Acta Histochem, 2004,106(4):269-278.
  • 5Nair R, Shaha C. Diethylstilbestrol induces rat spermatogenic cell apoptosis in vivo through increased expression of spermatogenic cell Fas/FasL system[J]. J Biol Chem, 2003, 278(8):6470-6481.
  • 6Fujisawa M, Ishikawa T. Soluble forms of Fas and Fas ligand concentrations in the seminal plasma of infertile men with varicocele[J]. J Urol, 2003, 170 (6 Pt 1):2363-2365.
  • 7Kilinc F, Guvel S, Kayaselcuk F, et al. p53 expression and apoptosis in varicocele in the rat tesis[J]. J Urol, 2004, 172(6 Pt 1):2475-2478.
  • 8Nakamuta N, Kobayashi S. Developmental expression of p63 in the mouse testis[J]. J Vet Med Sci, 2004, 66(6):681-687.
  • 9Widlak W, Benedyk K, Vydra N, et al. Expression of a constitutively active mutant of heat shock factor 1 under the control of testis-specific hst70 gene promoter in transgenic mice induces degeneration of seminiferous epithelium[J]. Acta Biochim Pol, 2003, 50(2):535-541.
  • 10Izu H, Inouye S, Fujimoto M, et al. Heat shock transcription factor 1 is involved in quality-control mechanisms in male germ cells[J]. Biol Reprod, 2004, 70 (1):18-24.

二级参考文献21

  • 1Meng X,Lindahl M,Hyvonen ME,et al.Regulation of cell fate decision of undifferentiated spermatogonia by GDNF [ J ].Science,2000,287(5457):1489-1493.
  • 2McLachlan RI,ODonnell L,Meachem SJ,et al.Hormonal regulation of spermatogenesis in primates and man:insights for development of the male contraceptive [ J ].J Androl,2002,23(2):149-162.
  • 3Themmen APN,Huhtaniemi IT.Mutations of gonadotropins and gonadotropin receptors:elucidating the physiology and pathophysiology of pituitary-gonadal function [ J ].Endoor Rev,2000,21(5):551-583.
  • 4Layman LC.Mutations in the follicle-stimulating hormone-beta(FSH beta)and FSH receptor genes in mice and humans[ J].Semin Reprod Med,2000,18(1):5-10.
  • 5Ramaswamy S,Plant TM.Operation of the follicle-stimulating hormone(FSH)-inhibin B feedback loop in the control of primate spermatogenesis[ J ].Mol Cell Endocrinol,2001,180(1-2):93-101.
  • 6Kinniburgh D,Anderson RA,Baird DT.Suppression of spermatogenesis with desogestrel and testosterone pellets is not enhanced by addition of finasteride[ J].J Androl,2001,22(1):88-95.
  • 7葛秦生主编.临床生殖内分泌学--男性与女性[M].北京:科学技术文献出版社,2001.762-800.
  • 8Wang C,Swerdloff RS.Male contraception [ J ].Best Pract Res Clin Obstet Gynaecol,2002,16(2):193-203.
  • 9Plant TM,Marshall GR.The functional significance of FSH in spermatogenesis and the control of its secretion in male primates [J].Endocr Rev,2001,22(6):764-786.
  • 10ODonnell L,Narula A,Balourdos G,et al.Impairment of spermatogonial development and spermiation after testosterone-induced gonadotropin suppression in adult monkeys(Macaca fascicularis)[J].J Clin Endoorinol Metab,2001,86(4):1814-1822.

共引文献27

同被引文献326

引证文献21

二级引证文献72

中华男科学杂志
2005年 第9期

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