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阵发性睡眠性血红蛋白尿症患者大颗粒淋巴细胞变化的研究

Large granular lymphocyte counts in paroxysmal nocturnal hemoglobinuria
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摘要 检测了32例正常人,32例阵发性睡眠性血红蛋白尿症(PNH)患者外周血大颗粒淋巴细胞(LGL)计数,发现:①PNH患者外周血LGL百分率及绝对值均显著低于正常对照组(P<0.001)。②发作期PNH患者外周血LGL百分率及绝对值均显著低于缓解期(P<0.001)。③缓解期PNH患者外周血LGL百分率及绝对值与正常对照组比较均无显著性差异(P>0.5)。结果提示:可以把LGL计数的变化作为判断PNH患者预后及疗效的指标。 LGL counts of peripheral blood in 32 healthy persons and 32 patients with PNH were measured.The results were as follows:①the LGL counts of 32 PNH patients were significantly lower than those in the control group(P<0.001),②the LGL counts of the patients who were really ill were lower than those of the patients in remission(P<0.001,③the LGL counts of the patients in remission did not differ significantly from those in the control group(P>0.5).The result indicated that the variation of LGL counts could be used as an index of prognosis and therapeutic effect.
出处 《河南医科大学学报》 1996年第2期87-88,共2页 Journal of Henan Medical University
关键词 血红蛋白尿 大颗粒淋巴细胞 PNH LGL计数 paroxysmal nocturnal hemoglobinuria large granular lymphocyte blood
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