摘要
为了解支气管剔除术产生的病理生理改变，作者进行了相应的动物实验。实验犬１６只分为：（１）实验组（１１只）：术前术后对比血气ＰＯ２，ＳａＯ２，ＣａＯ２及支气管造影。结果显示动物术后不发生血气紊乱，造影示相邻支气管位置仍正常，剔除支气管的肺处于扩张状态；（２）对照组（５只）采用相应肺段切除。与实验组组织学对比显示：实验组在剔除支气管肺段的肺组织呈轻度创伤性反应，无化脓现象，肺仍扩张，血管充盈，相邻健康肺段不受损害；而对照组肺段切除在健康肺段内出现较重的创伤反应，部分肺实变，有气肿形成。作者认为，支气管剔除较肺段切除治疗支气管扩张有早期消除残腔、手术损伤小、不损害健康肺组织等优点。
Sixteendogsweredividedtotwogroups:experimentalgroup(11)andcontrolgroup(5).Intheex-perimentagroup,thearterialbloodPO2SaO2,CaO2andbronchographywhichwerecomparedbetweenbeforeandafteroperationwerenormalandthebronchipositionshownbybronchographywasnotchangedandtheresiduallungaftebronchiextirpationwasstilinanexpansivestatus.Inthecontrolgroup,segmentalresectionswereperformed.Comparedwiththeexperimentalgroup,theresiduallungtissuesafterbronchiextirpationonlyhadlittlewoundrefectionandnoateledasisandexpandedwel.Nodestructionwasobservedintheneighbouringlungtissues.Butinthecontrolgroup,theheavydestruc-tion,consolidationandemphysemawereobservedintheadjacentnormallungtissues.Itisconclucedthattheextirpationofbronchicaneliminatetheresidualcavityearlyafteroperationandhaslessde-structionanddonotdestrcuttheadjacentnormallungtissues.
出处
《中华外科杂志》
CAS
CSCD
北大核心
1996年第3期180-181,共2页
Chinese Journal of Surgery
