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口服营养在慢性阻塞性肺疾病缓解期的应用研究 被引量:5

A study of application of oral nutrition in COPD patients in recovery stage
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摘要 选择肺心病患者44例,COPD患者42例,随机分成3组。Ⅰ组30例,每日服Ensurel3g和硒酸酯多糖100ng;Ⅱ组29例,每日服硒酸酯多糖100ng;Ⅲ组27例,每日服安慰剂胶囊1粒。共4周。复查结果显示:Ⅰ组的最大口腔吸气压升高27.2%,Ⅱ组升高18.7%,而Ⅲ组仅升高5.9%。Ⅰ、Ⅱ组与Ⅲ组比较有显著差异(P<0.05)。Ⅰ组的呼气高峰流速升高20.68%,PaO_2下降了10.70%,PaCO_2升高11.2%。Ⅱ、Ⅲ组无显著改变。Ⅰ和Ⅱ组的生活质量有明显提高,Ⅲ组无明显改变。提示口服营养具有加强呼吸肌肌力,改善呼吸功能的作用,不失为一种COPD患者康复治疗的方法。 patients with cor pulmonale and 42 with COPD were randomly divided into three groups :G Ⅰ、G Ⅱ and G Ⅲ.GⅠ consisted of 30 cases who have taken Ensure l3g and selenium in form of Kappa-Seleno carrageenan l00ng per day;GⅡ consisted of 29 cases who have taken selenium l00ng per day;G Ⅲ con sisted of 27 cases they were given placebo medicine one pill a day. After 4 weeks reexamines were taken. The results showed that:GI,the maximum inspiratory pressure(MIP)increased by 27.2%;G Ⅱ,increased by l8.7%;GⅢ,increased by 5.9%only(P<0.05).The pulmonary function and arterial gas analysis of G Ⅰ also made significantly progress,as follows:PEFR increased by 20. 68%; PaCO_2 de creased by l0.70%;PaO_2 increased by 11.2%;G Ⅱ and G Ⅲ have no significantly change. The quality of life of G Ⅰand GⅡ is significantly improved, after 4 weeks. The results suggested that the Ensure and selenium is able to improve the strength of respiratory muscles and the lung function.And it is a good methods of rehabilitation in patients with cor pulmonale and COPD.(Author's address:China-Japan Friendship Hospital,Beijing,100029)
机构地区 中日友好医院
出处 《中国康复医学杂志》 CAS CSCD 1996年第2期52-55,共4页 Chinese Journal of Rehabilitation Medicine
基金 "国家"八.五"攻关课题
关键词 肺心病 阻塞性肺疾病 呼吸压 硒酸酯多糖 Cor pulmonale COPD Oral nutrition Respiratory pressure Selenium
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