摘要
目的评价高压氧(HBO)综合治疗对小儿脑瘫运动功能的影响。方法采用随机区组配对的统计学方法,将57例小儿脑瘫患者(平均年龄2.3±1.3岁)分为两组:HBO治疗+常规治疗组(HBO组,n=31,0.16～0.20MPa)和常规治疗组(n=26)。评价治疗前、治疗1,2,3个疗程后肌张力(Ashworth指数)、总运动功能评分(GMF评分)。所有首次HBO治疗的患儿在3个月内接受30次(3个疗程)的HBO治疗。通过SPSS12.0统计软件对组内、组间数据进行Wilcoxon符号秩检验。结果HBO组:1个疗程后,Ashworth指数降低(P<0.05);2个疗程后,GMF评分降低(P<0.05)。其中<1岁组患儿的上述两个指标变化较其他两组明显(P<0.001)。结论HBO对轻症、早期(<1岁)脑瘫患儿的治疗效果最佳,对重症、病程长的患儿(>3岁)需要进行长疗程的HBO治疗。
Objective To evaluate of the effect of hyperbaric oxygenation （HBO） on the motor function of children with cerebral palsy （CP）. Methods 57 children with CP （ average age 2.3 ±1. 3 years） were divided by random block design into two groups： HBO group（ HBO ＋ conventional treatment） （ n =31, 0. 16～0.20 MPa） and control group （n = 26） （conventional treatment only）. And the muscle tension （Ashworth score） and motor function （Gross Motor Function Score, GMFS） at baseline and after 10,20,30 sessions of treatment were compared and evaluated. All the children in the HBO group received 30 sessions of HBO treatment in 3 months. Data analysis was made covariance and non-parametric test （Wilcoxon＇s）. with SPSS 12. 0. Results After 10 sessions, Ashworth score decreased （ P 〈 0. 05 ）, and 20 sessions, GMFS decreased （ P 〈 0. 05 ） in the HBO group. Significant improvements were made in children under 1 year （ P 〈 0.001 ）. Conclusions HBO treatment was significantly effective to children with mild CP and less than 1-year-old. As for children with severe CP and more than 3-year-old, it was necessary to take longer treatment with HBO.
出处
《中华航海医学与高气压医学杂志》
CAS
CSCD
2005年第3期151-154,共4页
Chinese Journal of Nautical Medicine and Hyperbaric Medicine
