摘要
目的了解贵州省水族人群β鄄地中海贫血的发病情况。方法采用“红细胞休克一管定量法”测定红细胞脆性,醋酸纤维素薄膜电泳分离测定,一分钟碱变性法测定HbF。结果在受检的1090人中,共检出β鄄地中海贫血携带者66例,检出率为6.06%,其中男性36例,女性30例,男女比例为1.2∶1。结论在贵州省三都地区水族人群中β鄄地中海贫血有较高的发生率,通过此次调查可使该人群对β鄄地中海贫血的严重危害性有所认识和引起有效的重视,这对开展优生优育,提高人口素质具有重要意义。
Objective Investigate the incidence of β-thalassemia in Guizhou San Du Shui people. Method Red cell shocking one tube method was used to detect the erythrocyte brittleness, the HbF and HbA2 were determined by the AM-electrophoresis and one minute Alkali denaturalization. Result Among the 1 090 samples, we found 66 cases of β-thalassemia carriers. The incidence was 6.055%, 36 cases were male, 30 cases were female, ratio was 1.2 ： 1. Condusion By investigating the situation of Guizhou minority Shui about β-thalassemia , we get the information that the incidence of β-thalassemia is very high in the area , the research is significative to make the Shui people know more about β-thalassemia and pay great intention to it, which is also significative to direct the local people＇s marriage, people＇s quality improvement.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2004年第1期75-76,共2页
Chinese Jouranl of Endemiology
基金
贵州省科委科研基金资助项目(19991201)
贵州省省长专项基金资助项目(2001)
