摘要
目的探讨硝普钠(SNP)复合芬太尼或瑞芬太尼在动脉导管未闭(PDA)手术中行控制性降压麻醉的有效性和安全性。方法先天性PDA患儿60例用SNP复合芬太尼(A组)或瑞芬太尼(B组)麻醉,监测不同时间血流动力学变化和并发症。结果B组心率稳定,降压迅速,SNP用量少,血流动力学变化和苏醒恢复状况均优于A组。结论瑞芬太尼持续麻醉能强化SNP的降压效果,减少并发症发生。
Objective To explore the efficacy and safety of sodium nitroprusside（SNP） with remifentanil or fentanyl used for controlled hypotension during the pediatric patent ductus arteriosus （PDA） operations. Methods Sixty children tmdergoing operation were randomly divided into SNP with fentanyl （A group） or remifentanil （B group）. Hemodynamic changes in different times and adverse reactions were observed. Results In B group, heart rate was stable and blood pressure declined quickly. The dose of SNP was fewer and hemodynamic changes and recovery from anesthesia were better in B group than in A group. Concision Remifentanil could potentiate the hypotensive effect of SNP and decrease adverse reaction.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2005年第11期1155-1156,共2页
Journal of Applied Clinical Pediatrics
基金
泸州医学院院级课题项目资助(04133)
关键词
降压
控制性
动脉导管未闭
硝普钠
controlled hypotension
patent duetus arteriosus
sodium nitroprusside
