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嗜酸粒细胞增多症53例临床分析 被引量:7

A clinical analysis of 53 cases of hypereosinophilia
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摘要 目的提高对嗜酸粒细胞增多症的认识.方法对北京协和医院1992-11~2005-02的嗜酸粒细胞增多症患者53例,予以回顾性分析.结果嗜酸粒细胞增多症的病因多种多样,反应性嗜酸粒细胞增多症中包括变态反应、感染、结缔组织疾病、肿瘤、嗜酸粒细胞性胃肠炎、呼吸系统疾病.特发性嗜酸粒细胞增多症18例表现为病程长、多系统累及,淋巴结肿大、脾大以及血栓的发生率高,白细胞、嗜酸粒细胞水平、免疫球蛋白(IgG)、C反应蛋白(CRP)水平较高.结论嗜酸粒细胞增多症的病因分布常广泛,临床表现各异,因此其诊断和鉴别诊断非常重要. Objective To comprehend the etiology and the clinical characteristics of hypereosinophilia. Methods The clinical data of 53 patients with hypereosinophilia admitted to Peking Union Medical College Hospital from November 1992 to February 2005 were analyzed. Results The causes of reactive hypereosinophilia included allergic diseases, infections, connective tissue diseases, malignant diseases, lung diseases, eosinophilie gastroenteritis, idiopathic hypereosinophilie syndrome had longer course of disease ; more organ involved than reactive causes. The incidence of lymph node enlargement, spleen enlargement and thrombus was higher than the reactive. IHES had higher level of white blood cell count, absolute eosinophilie count, IgG and CRP. Conclusion The etiology and clinical characteristics of hypereosi- nophilia are various, so the differential diagnosis of hypereosinophilia is very important.
作者 林洁 武永吉
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2005年第11期1017-1018,共2页 Chinese Journal of Practical Internal Medicine
关键词 嗜酸粒细胞增多症 特发性 Hypereosinophilia Idiopathic
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参考文献3

  • 1Brito-Babapulle F.The eosinophilias,including the idiopathic hypereosinophilic syndrome.Br J Haematol,2003,121(2):203-223
  • 2姚尔固.嗜酸粒细胞增多[A].见:邓家栋等主编.临床血液学[C].上海:上海科学技术出版社,2001.934-940.
  • 3Weller PF,Bubley GJ.The idiopathic hypereosinophilic syndrome.Blood,1994,83(10): 2759-2779

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