摘要
目的:建立注射用熊胆粉质量控制方法。方法:采用薄层色谱法对制剂中熊胆进行定性鉴别:用HPLC法测 定制剂中牛磺熊去氧胆酸含量。结果:薄层色谱中斑点清晰,易于识别:HPLC法精密度、重现性良好,牛磺熊去氧胆酸在 2．5～16μg内均较好的线性关系,加样回收率为99．75％,RSD为0．82％。结论:该法可有效控制注射用熊胆粉质量。
Objective：To establish method of quality control of injectable XIONGDAN powder. Methods：TLC was used to identify injectable XIONGDAN powder. The content of tauroursodeoxycholic acid in injectable XIONGDAN powder was determined by HPLC. Results： The spot in TLC was clear, easy to be recognized. HPLC was good in precision and reproducibility. HPLC exhibited a fine linear response of tauroursodeoxycholic acid ranged from 2.5-16μg. The average recovery was 99.75%, RSD 0.82%. Conclusion： The method can control the quality of injectable XIONGDAN powder effectually.
出处
《辽宁中医杂志》
CAS
北大核心
2005年第11期1189-1190,共2页
Liaoning Journal of Traditional Chinese Medicine
