摘要
为了评价联合化疗对多菌型麻风患者的疗效，对其１０年的结果进行了分析。４５７例多菌型患者在联合化疗中细菌指数（ＢＩ）下降情况示，联合化疗前ＢＩ≥３．０的经治、复发和新发患者，在治疗６０个月时，ＢＩ累积阴转率分别为８６．４％、６３．８％和８１．６％。６４２例患者在联合化疗和监测期分别有１０．４％和０．７％的患者发生麻风反应。对５５０例停药患者监测２５２０人年，发现１例经治患者复发。我们认为多菌型麻风患者完成联合化疗后，对其密切监测，及时发现反应和复发很有必要。
Inordertoevaluatethetherapeuticefectsofmultidrugtherapy(MDT)onmultibacil-laryleprosypatients,thechangeofbacteriologicalindexin457multibacilaryleprosypatientsonMDTwasstudied.Theresultsshowedthatthepatientspreviouslytreatedwithdapsone(DDS)alone,pa-tientsrelapsedafterDDSmonotherapyandnewlydiagnosedpatientswithBI≥3.0beforeMDT,60monthsafterMDT,theacumulativeratesofBInegativitywere86.4%,63.8%and81.6%respective-ly.Therewere67cases(10.4%)and4cases(0.7%)developedleprosyreactionintheperiodofMDTandfolowingup,respectively.Fivehundredandfiftycaseswerefolowedupfor1～8years,atotalof2520patient-years,andonepatientrelapsedatthethirdyearafterstoppingofMDT.Theauthorscon-siderthatitisnecesarytofolowupthepatientsaftercompletionofMDT,fortheearlydiagnosisofreversalreactionandrelapse.
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
1996年第4期255-257,共3页
Chinese Journal of Dermatology
