摘要
对两组病例，第１组６１例无精子症病人，进行精液细胞学与睾丸针吸细胞学检查；第２组１５例正常生育男性及４例无精子症病人，进行睾丸活检与精液细胞学检查。结果显示：第１组５３例（占８７％，５３／６１）精液中检出生精细胞，检出病例中精液细胞学与睾丸针吸细胞学所反映的生精细胞发育水平总符合率为９１％，经Ｘ２检验二者显著相关（Ｐ＜０．００５）；８例（占１３％）精液细胞学检查未见生精细胞的病例，考虑梗阴性无精子症，其中７例经精液生化指标证实，５例睾丸针吸细胞检查见精子。第２组两种方法所反映的生精细胞发育水平完全一致。说明精液细胞学检查既能很好反映睾丸生精状况，又能反映精道梗阴情况，是一种比较理想的判断睾丸生精功能及精道梗阻的无创伤性检查方法。
Objevtive To investigate the relationship between the examinations of semen cytology and testicle needle aspiration cytology,testicle biopsy cytology.Design Clinic and experimental studies.Settings Reproduction and Genetics Department of Nanjing General Hospital of Nanjing Command.Subjects 65 cases of azoospermia patients and 15 normal males.Methods Sixty-one patients were examinated with semen cytology and testicle needle aspiration cytology methods in the first group. The other four pateints and fifteen normal ferticle males were examined with semen cytology and testicle biopsy cytology methods in the second The developmental leavels of spermatogenic cells which were displayed were compared between the two examinations of each group.Results It was in 53 cases’semens(87%) that spermatogenic cells were found in the first group. The correspondence rate of semen cytology examination with testicle needle aspiration cytology examination was 91%. The chi-square test made clear that the two methods were significantly correlative(P<0.005). The other eight cases in which spermatogenic cells weren’t fount were considered obstractive azoospermia,seven cases of them were conformed by biochemical criterions, five by testile needle aspiration cytology method in which spermtozoa were found. In the second group, fifteen normal fertile males and four azoospermia peteints detected with semen cotylogy and testicle biopsy cytology methods were showen just the same developmental levels of spermatogenic cells. These demonstrated that the developmental leavels of spermatogenic cells which the two methods displayed were identical.Conclusion The semen cytology examination is competent for showing the spermatogenic status of testis and prompting obstructive situation of seminal ducts/tubules and is an untraumatic ideal method.
