摘要
目的探讨影响银屑病预后的相关因素。方法采用回顾性研究的方法,对350例住院银屑病患者的病历资料进行多因素非条件性Logistic回归分析。结果脂肪肝(P=0.0389,OR=2.244)对银屑病预后的影响有显著性(P<0.05),低蛋白血症(P=0.0005,OR=7.929)对银屑病预后的影响有高度显著性(P<0.01),高脂血症(P=0.0034,OR=0.211)成为银屑病预后的保护性因素,其影响有高度显著性(P<0.01),高尿酸血症(P=0.0858,OR=2.750)和特殊用药史(P=0.0658,OR=1.922)对银屑病预后的影响亦不容忽视。结论影响银屑病病情严重程度的因素主要为代谢系统紊乱,如脂肪肝、低蛋白血症、高尿酸血症,而高脂血症可能是银屑病的保护性因素。
Objective To investigate the risk factors of prognosis in psoriasis. Methods In this retrospective study, the risk factors of prognosis in psoriasis were analyzed by multivariate logistic regression with SAS 6.12 software. Results Fat liver（ P = 0. 0389, OR = 2. 244 ） and hypoproteinemia （ P = 0. 0005, OR = 7. 929） could aggravate the condition of psoriasis, however, hyperlipemia （ P = 0. 0034, OR = 0.211 ） could relaxe the condition of psoriasis, and hyperuricemia （ P = 0. 0858, OR = 2. 750 ） and special drug history （ P = 0. 0658, OR = 1. 922 ） could not be overlooked in the prognosis of psoriasis. Conclusion Many risk factors can influence the prognosis of psoriasis, fat liver, hypoproteinemia, hyperuricemia, special drug history could aggravated the condition of psoriasis,however,hyperlipemia might play a protective role in psoriasis.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2005年第10期604-606,共3页
The Chinese Journal of Dermatovenereology
关键词
银屑病
预后
危险因素
Psoriasis
Prognosis
Risk factors
